Nitric oxide (NO) in pathology of hypoxia/ischemia ? the ally or the enemy

• Authors: Rogalska Justyna
• Languages of publication: PL

Abstracts

EN

Nitric oxide (NO) has been found to play an important role as a signal molecule in many parts of the organism. However, under certain conditions, like hypoxia or ischemia, it acts as a cytotoxic effector molecule. It appears paradoxical that NO on the one hand acts as a physiological intercellular messenger and on the other can have damaging effects to cells. To make things even more complicated cytoprotective properties of NO are also described. Whether NO is useful or harmful depends on the rate and location of its production.

Keywords

EN

BLOOD FLOW; BRAIN; BRAIN DAMAGE; HYPOXIA; ISCHAEMIA; NITRIC OXIDE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2000
• Volume: 54
• Issue: 5
• Pages: 669-686

Contributors

author

Rogalska Justyna

• Document Type: ARTICLE
• Publication order reference: J. Rogalska, Zaklad Fizjologii Zwierzat UMK, ul. Gagarina 9, 87-100 Torun, Poland