Nociceptive dorsal root ganglion neurons

• Authors: P. Szulczyk , R. Rola , B. Szulczyk , G. Witkowski
• Languages of publication: PL

Abstracts

EN

Pain is generated by activation of specific dorsal root ganglion (DRG) neurons termed the nociceptive neurons. The nociceptive DRG neurons express 3 categories of ionic channels a. Channels gated by pain stimuli, b. Channels responsible for the transmission of information from sensory receptors to the spinal cord, c. Channels resposible for the release of neurotransmitters in the spinal cord. There is evidency that kinetic properties, molecular structure and functional significance of the ionic channels expressed in nociceptive DRG neurons are different compared to the other types of DRG neurons. The ionic channels are strictly controlled by receptors for neurotransmitters expressed in the plasma membrane of nociceptive DRG neurons.

Keywords

EN

DORSAL ROOT GANGLION; NOCICEPTIVE NEURON

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2002
• Volume: 56
• Issue: 3
• Pages: 361-375

Contributors

author

P. Szulczyk

author

R. Rola

author

B. Szulczyk

author

G. Witkowski

• Document Type: ARTICLE
• Publication order reference: P. Szulczyk, Katedra i Zaklad Fizjologiii Doswiadczalnej i Klinicznej Akdemii Medycznej, Krakowskie Przedmiescie 26/28, 00-927 Warszawa, Poland