Effect of increased intracranial pressure on arterial peripheral and cerebral blood pressure

• Authors: M. Dmowska , R. Schoenborn , E. Modrzejewski
• Languages of publication: EN

Abstracts

EN

The effect of increased intracranial pressure (ICP) on arterial peripheral (PBP) and cerebral blood pressure (CBP) was studied in 16 rabbits (New Zealand White). Changes of arterial blood pressure in peripheral and cerebral blood circulation were caused by a temporary (3 min) ICP increase. A raised ICP was obtained by infusing into the left lateral brain ventricle artificial cerebrospinal fluid at a pressure equal to 50, 100, and 150% of the initial CBP value. The experiments carried out showed that on reaching the initial CBP value, increased ICP induced Cushing response. The magnitude and duration of this reaction changed with increasing ICP, the intensity of the changes depending on the brain region in which the ICP increase was initiated.

Keywords

EN

ARTERIAL BLOOD PRESSURE; CEREBRAL BLOOD PRESSURE; CUSHING RESPONSE; INTRACRANIAL PRESSURE; PERIPHERAL BLOOD PRESSURE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Institute of Systematics and Evolution of Animals, Polish Academy of Sciences
• Journal: Folia Biologica
• Year: 1996
• Volume: 44
• Pages: 117-122

Contributors

author

M. Dmowska

author

R. Schoenborn

author

E. Modrzejewski

• Document Type: article
• Publication order reference: M.Dmowska, Department of Animal Physiology, Institute of Biology, M.Curie-Sklodowska University, Akademicka 19, 20-033 Lublin, Poland