Biotechnology of insect cell tissue culture

• Authors: A. Olejnik , W. Grajek
• Languages of publication: PL

Abstracts

EN

The commercial exploitation of the baculovirus expression system for heterologous protein or biopesticides production requires an efficient large-scale cultivation method. This review summarized recent developments concerning the scale-up of insect cell culture and baculovirus gene expression. We described novel bioreactor systems (stirred tank bioreactor, bioreactor airlift and cell-lift, membrane bioreactor), culture modes (batch, fed-batch, continuous) and different strategies used for cell cultivation and baculovirus replication.

Keywords

EN

BACULOVIRUS; BIOREACTOR; CELL CULTURE; INSECT

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 2003
• Issue: 1
• Pages: 176-192

Contributors

author

A. Olejnik

author

W. Grajek

• Document Type: REVIEW
• Publication order reference: A. Olejnik, Katedra Biotechnologii i Mikrobiologii Zywnosci, Akademia Rolnicza im. Augusta Cieszkowskiego, ul. Wojska Polskiego 48, 60-623 Poznan, Poland