Complex chromosomal rearrangement involving chromosomes 1, 4 and 22 in an infertile male: case report and literature review

• Authors: I. Salahshourifar , N. Shahrokhshahi , T. Tavakolzadeh , Z. Beheshti , H. Gourabi
• Languages of publication: EN

Abstracts

EN

Here we describe a rare case of an apparently balanced karyotype of 46, XY, t(1;22;4)(p22.3;q11.1;q31.1) in a infertile male with oligoastenoteratozoospermia (OAT). He was the second patient with complex chromosomal rearrangement (CCR) referred to our center because of infertility. We also review reports on 24 males carrying CCRs with spermatogenesis failure or a malformed child, to provide information on the reproductive outcome of male CCR carriers.

Keywords

EN

CHROMOSOMAL REARRANGEMENT; MALE INFERTILITY

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2009
• Volume: 50
• Issue: 1
• Pages: 69-72

Contributors

author

I. Salahshourifar

author

N. Shahrokhshahi

author

T. Tavakolzadeh

author

Z. Beheshti

author

H. Gourabi

• Document Type: ARTICLE
• Publication order reference: I. Salahshourifar, P. O. Box: 19395-4644, Reproductive Genetics Department, Reproductive Medicine Research Center, Royan Institute, ACECR, Tehran, Iran