Immunotherapeutic approaches in ocular inflammatory diseases

• Authors: S.K. Kurup , C.-C. Chan
• Languages of publication: EN

Abstracts

EN

This comprehensive review discusses immunotherapeutic approaches to ocular inflammatory diseases, updates information provided in the literature, and presents clinical experiences with an emphasis on autoimmune uveitis at the National Eye Institute, United States. Current medical and surgical therapeutic approaches, including medications such as corticosteroids, anti-metabolites, alkylating agents, calcineurin and purine synthesis inhibitors, biologics as well as some anti-infectious agents, are reviewed along with new modalities and experimental approaches. Most immunosuppressive therapies have significant adverse effects. Physicians must be familiar with the pharmacology of the available drugs and aware of the philosophies behind the treatment.

Keywords

EN

AUTOIMMUNE DISEASE; IMMUNOSUPPRESSION; INFLAMMATION; THERAPY

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 2005
• Volume: 53
• Issue: 6
• Pages: 484-496

Contributors

author

S.K. Kurup

author

C.-C. Chan

• Document Type: REVIEW
• Publication order reference: Shree K. Kurup, National Eye Institute, National Institutes of Health, Bethesda, MD 20892-1857, USA