Biotechnology to combat reactive oxygen species

• Authors: R. Nawrot , A. Gozdzicka-Jozefiak
• Languages of publication: PL

Abstracts

EN

Increased generation of reactive oxygen species (ROS) lies at the background of many diseases, including cancer. Numerous experimental data show that ROS play direct and indirect role in induction and promotion of cancer. Antioxidants, such as glutathione, bilirubin, urate, carotenoids, ascorbate, tocopherols, retinol, belong to nonenzymatic protective mechanisms against ROS antioxidents. A number of plants are rich source of egzogenic antioxidants. Genetic engineering methods are used to modify food plants in the hope that it will elevate their antioxidant content. The recent successful developments are -carotene-rich ?golden rice? and tomato. Intake of these plants could contribute to health benefits worldwide.

Keywords

EN

ASCORBIC ACID; BIOTECHNOLOGY; CANCER; CARCINOGENESIS; CAROTENOID; REACTIVE OXYGEN SPECIES; RETINOL; TOCOPHEROL

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 2002
• Issue: 2
• Pages: 88-101

Contributors

author

R. Nawrot

author

A. Gozdzicka-Jozefiak

• Document Type: REVIEW
• Publication order reference: A.Gozdzicka-Jozefiak, Zaklad Wirusologii Molekularnej UAM, ul. Miedzychodzka 5, 60-371 Poznan, Poland