Antisense oligonucleotides: from the bench to the patients

• Authors: T. Skorski , M. Nieborowska-Skorska , C. Szczylik , B. Calabretta
• Languages of publication: EN

Abstracts

EN

We describe here tha current state of progress toward gene-directed antisense-based cancer therapy targeting BCR/ABL, oncogene, primarily from the viewpoint of initial proof-of-concepts studies in animal models of human leukemias and phase I clinical investigations.

Keywords

EN

ANTISENSE STRATEGY; CANCER THERAPY; HUMAN LEUKEMIA; ONCOGENE

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1996
• Issue: 4
• Pages: 108-115

Contributors

author

T. Skorski

author

M. Nieborowska-Skorska

author

C. Szczylik

author

B. Calabretta

• Document Type: article
• Publication order reference: T.Skorski, Kimmel Cancer Center, Thomas Jefferson University, BLSB630, 233 South 10th Street, Philadephia, PA 19107, USA