Asymmetry in nucleotide composition of sense and antisense strands as a parameter for discriminating openreading frames as protein coding sequences

• Authors: S. Cebrat
• Languages of publication: EN

Abstracts

EN

Coding properties of yeast chromosomes were analysed and a strong asymmetry was found in nucleotide composition of sense and antisense strands. This property generates two very simple parameters [A]/[T] and [G]/[C] of the sense strand which could be used for discrimination of open reading frames as coding sequences with very high, statistically described level of significance. The paper contains a description of the method of ellipse of concentration in the two parameter space, which can close coding sequences inside, leaving a big fraction of noncoding sequences outside the ellipse.

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 1997
• Volume: 38
• Issue: 1
• Pages: 2-10

Contributors

author

S. Cebrat

• Document Type: article
• Publication order reference: S.Cebrat, Institute of Microbiology, Wroclaw University, Przybyszewskiego 63/77, 51-148 Wroclaw, Poland ,