Changes in the central respiratory rhythm following pharmacological blockade of the nucleus parabrachialis medialis in the rabbit

• Authors: K. Gromysz
• Languages of publication: EN

Abstracts

EN

Experiments were performed in halothane anesthetized, paralyzed, bilaterally vagotomized and artificially ventilated rabbits. Arterial blood pressure, expiratory carbon dioxide concentration, and electrical activity of the right phrenic nerve were recorded prior to and after xylocaine microinjection to the left nucleus parabrachialis medialis (NPBM). The location of the xylocaine blockade was verified histologically. It was found that blockade of the NPBM results in a decelerated respiratory rhythm due to lengthening of both phases of the respiratory cycle. These results do not corroborate the role of NPBM in the regulation of respiration as postulated by Bertrand and Hugelin (1971). ugelin (

Keywords

EN

APNEUSIS; NUCLEUS PARABRACHIALIS MEDIALIS; RESPIRATORY RHYTHM

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Marceli Nencki Institute of Experimental Biology, Polish Academy of Sciences
• Journal: Acta Neurobiologiae Experimentalis
• Year: 1997
• Volume: 57
• Issue: 4
• Pages: 339-343

Contributors

author

K. Gromysz

• Document Type: article
• Publication order reference: H.Gromysz, Department of Neurophysiology, Polish Academy of Sciences Medical Research Centre, 5 Pawinski St., 02-106 Warsaw, Poland