IMPACT OF EXCIPIENTS ON PHARMACEUTICAL AVAILABILITY OF FOLIC ACID FROM TABLETS

• Authors: Aneta Ostróżka-Cieślik , Barbara Dolińska , Florian Ryszka
• Languages of publication: EN

Abstracts

EN

The impact of excipients contained in individual formulations on the pharmaceutical availability of folic acid was investigated. The release rate of the active substance and the disintegration time of the tablets were analysed. It has been found that in the presence of sorbitol, glucose and starch, 100% of folic acid is released within 60 minutes, and in the presence of lactose and starch - 95%, and the release rates for them are 0.0717 min-1 and 0.0555 min-1 respectively.

Keywords

EN

folic acid; dietary supplements; dissolution testing

• Journal: Acta Poloniae Pharmaceutica - Drug Research
• Year: 2018
• Volume: 75
• Issue: 4
• Pages: 959-963

Dates

published

2018-08-31

Contributors

author

Aneta Ostróżka-Cieślik

author

Barbara Dolińska

author

Florian Ryszka

Identifiers

DOI

10.32383/appdr/78082