T1 and T2 Relaxation Times from Substantia Nigra in Parkinson's Disease and Control

• Authors: R. Kuliński , K. Szlachta , J. Gałązka-Friedman , A. Friedman
• Languages of publication: EN

Abstracts

EN

The diagnosis of Parkinson's disease, and also other neurodegenerative disorders, is based on clinical examination. Many attempts are undertaken to find a test that could confirm this clinical diagnosis. Many hopes were attributed to magnetic resonance imaging but its importance remains obscure. The aim of this study was to compare T1 and T2 relaxation times from substantia nigra of patients with clinical diagnosis of Parkinson's disease and age-matched controls. A decrease of T2 (54.5 ± 1.4 ms vs. 58.0 ± 1.5 ms) in Parkinson's disease vs. control was found with confidence level of 5%. T1 did not differ significantly between Parkinson's disease and control (624 ± 17 ms vs. 614 ± 21 ms).

Keywords

EN

87.19.L-

Discipline

• 87.19.L-: Neuroscience

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2014
• Volume: 125
• Issue: 4
• Pages: 869-871

Dates

published

2014-04

Contributors

author

R. Kuliński

• Department of Nuclear Medicine and Magnetic Resonance, Bródno Regional Hospital, Warszawa, Poland

author

K. Szlachta

• Faculty of Physics, Warsaw University of Technology, Poland

author

J. Gałązka-Friedman

• Faculty of Physics, Warsaw University of Technology, Poland

author

A. Friedman

• Department of Neurology, Medical University of Warszawa, Poland

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Identifiers

DOI

10.12693/APhysPolA.125.869