Identification of Gastric Cancer from Speckle Patterns

• Authors: C. Andrade-Eraso , M. Patiño-Velasco , J. Vásquez-López , J. León , G. Bolaños-Pantoja , M. Trivi
• Languages of publication: EN

Abstracts

EN

Speckle technique is based on the light intensity distribution randomly formed when a laser light is reflected on a rough surface, creating a pattern of illuminated grains (constructively) and dark (destructive) on scales of 1 μm. When the samples are displaced or deformed, the speckle pattern is altered. In this paper we present speckle patterns obtained from samples of gastric mucosa that is physically altered for the carcinogenesis process. Biopsies were studied with different diagnoses and were grouped according to the characteristics of speckle patterns. Speckle patterns were obtained by illuminating the samples with green laser. Morphological parameters of the speckle patterns reveal existence of 3 descriptors: the average grain size, hydraulic radius and the radio of the Weddel disc, which showed a high, intermediate and low value. The comparison shows agreement between the histopathological diagnosis and the values obtained by the speckle technique, making this technique emerge as a new classification system for quantitative diagnosis of precancerous lesions.

Keywords

EN

78.68.+m; 42.87.-d; 87.50.W-

Discipline

• 78.68.+m: Optical properties of surfaces
• 87.50.W-: Optical/infrared radiation effects
• 42.87.-d: Optical testing techniques

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2012
• Volume: 121
• Issue: 1
• Pages: 62-64

Dates

published

2012-01

Contributors

author

C. Andrade-Eraso

• Grupo de Óptica y Laser, Departamento de Física, Universidad del Cauca, Popayán, Colombia

author

M. Patiño-Velasco

• Grupo de Óptica y Laser, Departamento de Física, Universidad del Cauca, Popayán, Colombia

author

J. Vásquez-López

• Grupo de Óptica y Laser, Departamento de Física, Universidad del Cauca, Popayán, Colombia
• Departamento Morfología, Facultad de Ciencias de la Salud, Universidad del Cauca, Popayán, Colombia

author

J. León

• Centro de Investigaciones en Ingeniería y Organizaciones, Grupo de Investigaciones en Ciencias Aplicadas, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia

author

G. Bolaños-Pantoja

• Grupo de Física de Bajas Temperaturas, Departamento de Física, Universidad del Cauca, Popayán, Colombia

author

M. Trivi

• Centro de Investigaciones Ópticas (CONICET La Plata - CIC) and UID Optimo, Dpto. Ciencias Básicas, Facultad de Ingeniería, Universidad Nacional de La Plata, Casilla de Correo 3, 1897 Gonnet-La Plata, Argentina

References

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Identifiers

DOI

10.12693/APhysPolA.121.62