Point Investigation Method for Cancer Changed Tissues

• Authors: Ł. Kłonowski , Z. Kulas , E. Bereś-Pawlik , M. Rząca , R. Czarnecki , Z. Grzebieniak
• Languages of publication: EN

Abstracts

EN

In this paper we describe the method of point investigation for cancer changed tissues with application of fluorescence phenomenon. The measurements have been made using a specially constructed scanning setup and fiber sensors. The experiment with investigation of endogenous fluorescence has been made on different types of slide tissues (e.g. breast and intestine tumor or precancerous and pathological skin tissues). The obtained spectral characteristics of fluorescence, with typical intensity peaks in 480-520 nm range, have explicitly outlined healthy and pathologically changed areas. The intensity of detected fluorescence determines the evaluation of disease advancement. Moreover, the ability to scan the surface of a tissue sample with constantly moving step of scanning setup in X-Y axis allows us to present the results in a spatial distribution of fluorescence intensity.

Keywords

EN

87.57.-s; 87.57.R-; 87.57.nm; 87.19.xu; 87.19.xj

Discipline

• 87.57.-s: Medical imaging
• 87.57.R-: Computer-aided diagnosis
• 87.19.xj: Cancer
• 87.19.xu: Gastrointestinal diseases
• 87.57.nm: Segmentation

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2010
• Volume: 118
• Issue: 6
• Pages: 1174-1176

Dates

published

2010-12

Contributors

author

Ł. Kłonowski

• Institute of Telecommunications, Teleinformatics and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

author

Z. Kulas

• Institute of Telecommunications, Teleinformatics and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

author

E. Bereś-Pawlik

• Institute of Telecommunications, Teleinformatics and Acoustics, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland

author

M. Rząca

• Oncology Department, Regional Specialistic Hospital, Kamińskiego 73a, 51-124 Wrocław, Poland

author

R. Czarnecki

• Oncology Department, Regional Specialistic Hospital, Kamińskiego 73a, 51-124 Wrocław, Poland

author

Z. Grzebieniak

• Oncology Department, Academy Clinical Hospital, Borowska 213, 50-556 Wrocław, Poland

References

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Identifiers

DOI

10.12693/APhysPolA.118.1174