Modern External Beam Radiotherapy Techniques - Intensity Modulated Radiotherapy

• Authors: A. Śladowska
• Languages of publication: EN

Abstracts

EN

External beam radiotherapy is a complex cancer radiotherapy technique involving three-dimensional conformal and intensity-modulated radiation therapy high-energy X-ray beam delivery to tumour volumes where dose distributions and treatment plan optimisation, including inverse planning, are applied. Examples of clinical treatment plans using 3D conformal and intensity-modulated radiotherapy techniques for patients with tumours located in the regions of head and neck (right tonsil carcinoma) and pelvis (prostate) were evaluated and compared. An intensity-modulated radiotherapy plan for a patient with arm cancer, untreatable with the 3D conformal radiation therapy technique, is also presented. Comparison of dose distributions showed that with the intensity-modulated radiotherapy technique dose homogeneity within the target volume was improved and dose to normal tissues and organ-at-risk structures reduced. Significant reductions in the mean and maximum doses to the spinal cord (head and neck) and rectum (prostate) were also achieved. Due to the geometrical issues, in all patients, improvement in dose distribution was evident with the intensity-modulated radiotherapy technique, especially for concave dose distributions.

Keywords

EN

87.56.-v; 87.56.J-; 87.56.N-; 87.56.jk

Discipline

• 87.56.-v: Radiation therapy equipment
• 87.56.jk: Field shaping
• 87.56.N-: Beam intensity modifications
• 87.56.J-: Collimation

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2009
• Volume: 115
• Issue: 2
• Pages: 586-590

Dates

published

2009-02

Contributors

author

A. Śladowska

• Maria Skłodowska-Curie Memorial Institute, Centre of Oncology, Cracow Branch, Garncarska 11, 31-115 Kraków, Poland

References

• 1. S. Webb, The Physics of Three-Dimensional Radiation Therapy: Conformal Radiotherapy, Radiosurgery and Treatment Planning, Institute of Physics Publishing, Bristol 1993
• 2. S. Webb, The British J. Radiol. 76, 678 (2003)
• 3. W. Schlegel, A. Mahr, 3D Conformal Radiation Therapy - Multimedia Introduction to Methods and Techniques, Multimedia CD-ROM Springer, New York 2001
• 4. New Technologies in Radiation Oncology, Eds. W. Schlegel, T. Bortfeld, A.-L. Grosu, Springer, New York 2006
• 5. K.S. Chao, S. Apisarnthanarax, G. Ozyigit, Practical Essentials of Intensity Modulated Radiation Therapy, 2nd ed., Lippincott, Williams & Wilkins, Philadelphia 2005
• 6. ICRU, Prescribing, Recording and Reporting Photon Beam Therapy, Report 50, International Commission on Radiation Units and Measurements, Washington, DC 1993
• 7. ICRU, Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50), Report 6, International Commission on Radiation Units and Measurements, Washington, DC 1999
• 8. S. Bin, Y. Shiao, The Oncologist 4, 422 (1999)
• 9. Image Guided IMRT, Eds. T. Bortfeld, R. Schmidt-Urlich, W. de Neve, D.E. Wazer, Springer, Berlin 2006
• 10. M. Guckenberger, F. Pohl, K. Baier, J. Meyer, D. Vondermark, M. Flentje, Radiother. Oncol. 79, 59 (2006)
• 11. C. Fiorino, C. Gianolini, A.E. Nahum, Phys. Med. Biol. 48, 2603 (2003)
• 12. B. Longobardi, E. De Martin, C. Fiorino, I. Dell'oca, S. Broggi, G. Cattaneo, R. Calandrino, Radiother. Oncol. 77, 148 (2005)
• 13. W. Bar, M. Shwarz, M. Alber, B.J. Mijnheer, C. Rash, C. Schneider, F. Nusslin, E.M. Damen, Radiother. Oncol. 69, 251 (2003)
• 14. K.M. Alektiar, L. Hong, M.F. Brennan, C. Della-Biancia, S. Singer, Int. J. Radiation Oncology Biol. Phys. 68, 458 (2007)
• 15. L. Hong, K.M. Alektiar, M. Hunt, E. Venkatraman, S. Leibel, Int. J. Radiation Oncology Biol. Phys. 59, 752 (2004)

Identifiers

DOI

10.12693/APhysPolA.115.586