Investigation of Trace Element Concentration in Diabetic Rat's Tissues

• Authors: J. Kowalska , M. Krośniak , R. Gryboś , W. Kwiatek
• Languages of publication: EN

Abstracts

EN

Diabetes is one of the most frequent diseases in developing countries and thus there is a significant interest in diabetes related studies. It was found that vanadium compounds have glucose-lowering properties in diabetes and therefore it is very important to estimate the vanadium dose in diabetes treatment. On the other hand, the proper estimation of vanadium concentration is important due to side effects that occur in vanadium supplementation. In this study the influence of V(IV) and V(V) compounds with different ligands on the concentration of K, Ca, Mn, Fe, Cu, and Zn in selected rat's tissues was investigated by means of proton induced X-ray emission technique. As a result of the measurements it was found that the concentration of vanadium depends on the organ. The highest value was determined in spleen while the lowest in pancreas. It was also found that the concentration of other elements depends on the presence of vanadium and its concentration. The most meaningful influence of vanadium presence was on iron concentration in spleen, on copper and zinc in kidney, and on manganese in pancreas.

Keywords

EN

29.30.Ep; 78.70.En; 87.19.X-

Discipline

• 87.19.X-: Diseases
• 78.70.En: X-ray emission spectra and fluorescence
• 29.30.Ep: Charged-particle spectroscopy

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2009
• Volume: 115
• Issue: 2
• Pages: 556-560

Dates

published

2009-02

Contributors

author

J. Kowalska

• Department of Applied Spectroscopy, Institute of Nuclear Physics, PAS, Radzikowskiego 152, 31-342 Kraków, Poland

author

M. Krośniak

• Department of Food Chemistry and Nutrition, Medical College Jagiellonian University, Kraków, Poland

author

R. Gryboś

• Faculty of Chemistry, Jagiellonian University, Kraków, Poland

author

W. Kwiatek

• Department of Applied Spectroscopy, Institute of Nuclear Physics, PAS, Radzikowskiego 152, 31-342 Kraków, Poland

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Identifiers

DOI

10.12693/APhysPolA.115.556