Studies on sintering process of synthetic hydroxyapatite

• Authors: Dagmara Malina , Kamila Biernat , Agnieszka Sobczak-Kupiec
• Languages of publication: EN

Abstracts

EN

In this study the effect of sintering process in different temperatures on microstructure and morphological properties of sintered hydroxyapatite (HAp) was investigated. HAp powder was prepared by wet precipitation method from following reagents: Ca(OH)2 + H3PO4 in an alkaline conditions. Thermal analysis (TA), X-Ray diffraction method (XRD), FT-IR spectrometry (FT-IR) and scanning electron microscopy (SEM) were used to elaborate the phase composition and properties of sintered HAp samples and raw HAp powder as well. The total and apparent density and total porosity of sintered compacts, shrinkage and weight loss during the sintering were also measured. The results show that there is a difference in sintering behavior of synthetic hydroxyapatites depending on sintering temperature. The main differences refer to the loss of mass, shrinkage, changes in porosity and density of the investigated materials.

Keywords

EN

calcium phosphates; hydroxyapatite; sintering process; wet synthesis

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2013
• Volume: 60
• Issue: 4
• Pages: 851-855

Dates

published

2013

received

2013-10-28

revised

2013-12-20

accepted

2013-12-20

Contributors

author

Dagmara Malina

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Kraków, Poland

author

Kamila Biernat

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Kraków, Poland

author

Agnieszka Sobczak-Kupiec

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Kraków, Poland

References

• Champion E (2013) Sintering of calcium phosphate bioceramics. Acta Biomater 9: 5855-5875.
• Fathia MH, Hanifia A, Mortazavi V (2008) Preparation and bioactivity evaluation of bone-like hydroxyapatite nanopowder. J Mater Process Tech 202: 536-542.
• Gibson IR, Ke S, Best SM, Bonfield W (2001) Effect of powder characteristics one the sinterability of hydroxyapatite powders. J Mater Sci - Mater Med 12: 163-171.
• Gu YW, Loh NH, Khor KA, Tor SB, Cheang P (2002) Spark plasma sintering of hydroxyapatite powders. Biomaterials 23: 37-43.
• Joschek S, Nies B, Krotz R, Göpferich A (2000) Chemical and physicochemical characterization of porous hydroxyapatite ceramics made of natural bone. Biomaterials 21: 1645-1658.
• Juang HJ, Hon MH (1996) Effect of calcination on sintering of hydroxyapatite. Biomaterials 17: 2059-2064.
• Lazić S, Zec S, Miljević N, Milonjić S (2001) The effect of temperature on the properties of hydroxyapatite precipitated from calcium hydroxide and phosphoric acid. Thermochim Acta 374: 13-22.
• Lee JB, Kim SE, Heo DN Kwon IK (2010) In vitro characterization of nanofibrous PLGA/gelatin/hydroxyapatite composite for bone tissue engineering. Macromol Res 18: 1195-1202.
• LeGeros RZ (2008) Calcium Phosphate-Based Osteoinductive Materials. Chem Rev 108: 4742-4753.
• Malina D, Sobczak-Kupiec A, Wzorek Z, Kowalski Z (2011) Nanotechnology in dentistry. Inżynieria Stomatologiczna - Biomateriały 8: 24-26 (in Polish).
• Prokopiev O, Sevostianov I (2006) Dependence of the mechanical properties of sintered hydroxyapatite on the sintering temperature. Mater Sci Eng A 431: 218-227.
• Raynaud S, Champion E, Bernache-Assollant D, Thomas P (2002) Calcium phosphate apatites with variable Ca/P atomic ratio I. Synthesis, characterization and thermal stability of powders. Biomaterials 23: 1065-1072.
• Sobczak A, Kowalski Z (2007) Materiały hydroksyapatytowe stosowane w implantologii. Czasopismo Techniczne 8: 149-158 (in Polish).
• Sobczak-Kupiec A, Janicki T, Malina D, Wzorek Z (2011) Hydroksyapatyt - uniwersalny biomateriał dla medycyny i stomatologii. Inżynieria Stomatologiczna - Biomateriały 8: 37-41 (in Polish).
• Sobczak-Kupiec A, Wzorek Z (2012) The influence of calcination parameters on free calcium oxide content in natural hydroxyapatite. Ceram Int 38: 641-647.
• Sopyan I, Mel M, Ramesh S, Khalid KA (2007) Porous hydroxyapatite for artificial bone applications. Sci Tech Adv Mater 8: 116-123.
• Thangamani N, Chinnakali K, Gnanam FD (2002) The effect of powder processing on densification, microstructure and mechanical properties of hydroxyapatite. Ceram Int 28: 355-362.
• Zhang M, Liu Ch, Sun J, Zhang X (2011) Hydroxyapatite/diopside ceramic composites and their behaviour in simulated body fluid. Ceram Int 37: 2025-2029.