Homocysteine level in urine of autistic and healthy children

• Authors: Joanna Kałużna-Czaplińska , Monika Michalska , Jacek Rynkowski
• Languages of publication: EN

Abstracts

EN

Homocysteine is an amino acid which plays several important roles in human physiology and is an important biomarker for possible deficiencies of various vitamins (vitamin B6 and B12, folic acid). In this work GC-MS method was used to determine the levels of homocysteine in the urine of autistic and healthy children. The levels of homocysteine in urine samples from 34 autistic and 21 healthy children were 2.36 ± 1.24 and 0.76 ± 0.31 (mmol∙mol-1 creatinine), respectively. The higher level of homocysteine in autistic children may indicate deficiencies of folic acid and vitamins B6 and B12 in nutrition of these children. The results of this work were taken into consideration in the nutrition of autistic children treated in the Navicula Centre of Diagnosis and Therapy of Autism in Łódź (Poland).

Keywords

EN

GC/MS; urine; autism; homocysteine

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2011
• Volume: 58
• Issue: 1
• Pages: 31-34

Dates

published

2011

received

2010-05-06

revised

2011-01-20

accepted

2011-01-24

(unknown)

2011-03-11

Contributors

author

Joanna Kałużna-Czaplińska

• Institute of General and Ecological Chemistry, Department of Chemistry, Technical University of Łódź, Łódź, Poland

author

Monika Michalska

• Institute of General and Ecological Chemistry, Department of Chemistry, Technical University of Łódź, Łódź, Poland

author

Jacek Rynkowski

• Institute of General and Ecological Chemistry, Department of Chemistry, Technical University of Łódź, Łódź, Poland

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