Solid Fly-ash:PTS catalyzed synthesis, spectral studies and antimicrobial activities of some 1,3-diarylpropenones

• Authors: R. Arulkumarana , G. Vanangamudia , D. Kamalakkannana , R. Sundararajana , S. Vijayakumara , K. Thirumurthyb , P. Mayavelb , G. Thirunarayanan
• Languages of publication: EN

Abstracts

EN

The green catalyst Fly-ash:PTS has been prepared and characterized by IR and SEM analysis. Using this catalyst some aryl chalcones have been synthesized by aldol condensation of aryl methyl ketone and substituted benzaldehydes. It has been observed that this reaction yields more than 85% of the product. These chalcones have been characterized by their physical constants and spectral data following the procedures published in literature. The effect of substituents on the spectral data of the chalcones, synthesized, has been studied using single and multi-regression analysis with Hammett equation. The antibacterial and antifungal activities of these chalcones have been studied using Bauer-Kirby method.

Keywords

EN

Chalcones; Greener synthesis; Fly-ash:PTS; UV spectra; IR spectra; NMR spectra; Hammett correlation; antibacterial activity; antifungal activity

• Publisher: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
• Journal: Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
• Year: 2012
• Volume: 67
• Issue: 1-2
• Pages: 45-77

Dates

published

1 - 12 - 2012

online

25 - 01 - 2014

Contributors

author

R. Arulkumarana

• PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram-608102, India

author

G. Vanangamudia

• PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram-608102, India

author

D. Kamalakkannana

• PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram-608102, India

author

R. Sundararajana

• PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram-608102, India

author

S. Vijayakumara

• PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram-608102, India

author

K. Thirumurthyb

• Department of Chemistry, Annamalai University, Annamalainagar-608002, India

author

P. Mayavelb

• Department of Chemistry, Annamalai University, Annamalainagar-608002, India

author

G. Thirunarayanan

• Department of Chemistry, Annamalai University, Annamalainagar-608002, India

References

• [1] G. Thirunarayanan, G. Vanangamudi, V. Sathiyendiran and K. Ravi, Indian J. Chem., 50B(4),593, (2011).
• [2] G. Thirunarayanan, G. Vananagamudi, Arkivoc., 12, 58, (2006).
• [3] G. Thirunarayanan, J. Indian Chem. Soc., 85, 447, (2008).
• [4] G. Thirunarayanan, G. Vananagamudi, E-J. Chem., 4, 90, (2007).
• [5] G. Thirunarayanan, Indian J. Chem., 46B, 1511, (2007).
• [6] S. Kobayashi, H. Kiyohara and M. Yamaguchi, J. Am. Chem. Soc., 133, 708, (2011).
• [7] W. Li, W. Wu, J. Yang, X. Liang, J. Ye, Synthesis., 1085, ( 2011).
• [8] G.A. Morris and S.T. Nguyen, Tetrahedron Lett., 42, 2093, (2001).[Crossref]
• [9] Z. Wang, L. Xu, Z. Mu, C. Xia, H. Wang, J. Mol. Catal., 218A, 157, (2004).
• [10] S. H. Leung, S.A. Angel, J. Chem. Educ., 81, 1492, (2004).
• [11] G. Thirunarayanan, J. Korean Chem. Soc., 52(4) 369, (2008).
• [12] G. Thirunarayanan, P. Ananthakrishna Nadar, J. Indian Chem. Soc., 83(11) 1107, (2006).
• [13] G. Thirunarayanan, P. Mayavel, K. Thirumurthy, Spectrochim Acta., 91A, 18, (2012).
• [14] D.R. Palleros, J. Chem. Educ., 81(9), 1345, (2004).
• [15] S.A. Basaif, T.R. Sobahi, A.K. Khalil, M.A. Hassan, Bull. Korean Chem. Soc., 26(11), 1677, (2005).
• [16] Q. Xu, Z. Yang, D. Yin, F. Zhang, Catal. Commun., 9(1), 1579, (2008).
• [17] P. Kumar, S. Kumar, K. Husain, A. Kumar, Chin. Chem. Lett., 22(1), 37, (2011).
• [18] Z. Zhang, Y.W. Dong, G.W. Wang, Chem. Lett., 32(10), 966, (2003).
• [19] H.E. Blackwell, Current Opinion in Chem. Biol., 10(3), 203, (2006).
• [20] G. Thirunarayanan, “Proceedings of the 46th Annual convention of Chemists and International conference on recent research trends in chemical sciences” No. ORG OP5, p. C13, (2009).
• [21] B. Krishnakumar, R. Velmurugan, M. Swaminathan, Catal. Commun., 12(5), 375, (2011).
• [22] B.F.G. Johnson, J. Lewis, G.R. Stephenson, E.J.S. Vichi, J. Chem.Soc., Dalton Trans., 369 (1978).
• [23] Kiadó, J. Thermal Anal. Calorimetry., 76, 193, (2010).
• [24] Y. Xiuying, P. An-shun, J. Linyi Teachers Coll., 23, O621.3, 2004)
• [25] P. Salehi, M. Dabiri, M. A. Zolfigol, M. A. B. Fard, J. Braz. Chem.Soc. 15(5), 773, (2004).
• [26] D. Kamalakkannan, G. Vanangamudi, R. Arulkumaran, K. Thirumurthy, P. Mayavel, G.Thirunarayanan, Elixir Org. Chem., 46, 8251, (2012).
• [27] P.T. Cardew, M.S. Ie, Chap. 2. Membrane technologies, pp. 2-20, (1998).
• [28] R.J. Butcher, J.P. Jasinsky, B. Narayanan, K. Lakshmana, H.S. Yathirajan, Acta. Cryst., E64, o4919, (2008).
• [29] Chem Spider Compound ID: 4650199.
• [30] FRPSAX Farmaco, Edizione Scientifica., 25, 860, (1970).
• [31] G. Vanangamudi, M. Subramanian , P. Jayanthi, R. Arulkumaran, D.Kamalakkannan, G. Thirunarayanan, Arab. J. Chem., doi:10. 1016/j.arabjc.2011.07.019[Crossref]
• [32] G. Thirunarayanan, G. Vanangamudi, M. Subramanian, U. Umadevi, S. P. Sakthinathan, R. Sundararajan, Elixir Org. Chem., 39, 4643, (2011).
• [33] M. Subramanian Ph.D. Thesis, Thiruvalluvar University, Vellore, 2011.
• [34] C.G. Swain and E.C. Lupton Jr, J. Am Chem Soc., 90, 4328, (1968).[Crossref]
• [35] M. Sivakumar, S. Phrabu Sreeneivasan, V. Kumar and M. Doble, Bioorg. Med. Chem. Lett., 17(10), 3169, (2007).
• [36] K.L. Lahtchev, D.I. Batovska, St.P. Parushev, V.M. Ubiyvock, A.A.Sibirny, Eur.J. Med. Chem., 43(1), 1, (2008).
• [37] V.S. Parmer, K.S. Bishit, R. Jain, S. Singh, S.K. Sharma, S. Gupta, S. Malhotra, O.D. Tyagi, A. Vardhan, H.N. Pati, D.V. Berghe, A.J. Vlietinek, Indian J. Chem., 35B, 220, (1996).
• [38] G. Thirunarayanan, S. Surya, S. Srinivasan, G. Vanangamudi, V. Sathyendiran, Spectrochim Acta., 75A, 152, (2010). 39] G. Thirunarayanan, G. Vanangamudi, M. Subramanian, Elixir. Org.Chem., 43, 6987, (2012).
• [40] J.N. Dominguez, C. Leon and J. Rodrigues, IL Farmaco., 60(4), 307, (2005).
• [41] Y.M. Lin, Y. Zhon, M.T. Flavin, L.M. Zhon, W. Ne, F.C. Chen, Bioorg. Med. Chem., 10(8), 2795, (2002).
• [42] J. Deng, T. Sanchez and Q.A.M. Lalith, Bioorg. Med. Chem., 15(14), 4985, (2007).[Crossref]
• [43] M.W. Weber, L.A. Hunsaker, S.F. Abcouwer, L.M. Decker, D.L. Vander Jagat, Bioorg. Med. Chem., 13, 3811, (2005).
• [44] W. Bauer, W.M. Kirby, J.C. Sherris, M. Truck, Am. J. Clin. Pathol., 45, 493, (1996).

Identifiers

DOI

10.2478/v10063-012-0003-8