Adaptation of Quality of Life Module EORTC QLQ-CR29 for Polish Patients with Rectal Cancer - Initial Assessment of Validity and Raeliability

• Authors: Wojciech Nowak , Beata Tobiasz-Adamczyk , Piotr Brzyski , Jerzy Sałówka , Dagmara Kuliś , Piotr Richter
• Languages of publication: EN

Abstracts

EN

Heath related quality of life has been an important object of interest in the clinical practice, focused on assessment of treatment effects from patient's point of view, with particular emphasis placed on effect of treatment on daily patient functioning. Concept of health-related quality of life needs valid and reliable instruments.The aim of the study was to present the process of validation of a new version of EORTC QLQ-CR29 module in Polish patients suffering from rectal cancer.Material and methods. EORTC QLQ-CR29 module comprises 29 questions, and was adapted to Polish cultural conditions based on EORTC procedure. Data collected from 20 patients were analyzed, their agreement with theoretical and empirical structure was assessed. Convergent and discriminant validity were analyzed with multi trait scaling.Reliability was assessed with Cronbach alpha coefficient. Known group validity was assessed in terms of differences between men and women, and between stoma and non-stoma patients. Exact Mann-Whitney test was used. P values lower than 0.05 were considered significant.Results. Scales built on bases of empirical model of module had higher validity and reliability than those based on theoretical model.There were no significant differences between men and women in health-related quality of life. Significantly higher values were observed in non-stoma patients on body image scale and for leakage of stool item. Reversed relationship was observed in case of abdominal and buttocks pain, as well as embarrassment because of bowel movements.Conclusions. Module CR29 is a valid and reliable tool, which enables standardized measurement of treatment effects, suggested for use as main tool measuring impact of disease itself and applied treatment on health-related quality of life of rectal cancer patients.

Keywords

EN

rectal cancer; health-related quality of life; EORTC QLQ-CR29; validity; reliability

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2011
• Volume: 83
• Issue: 9
• Pages: 502-510

Dates

published

1 - 9 - 2011

online

5 - 10 - 2011

Contributors

author

Wojciech Nowak

• 3rd Department of General Surgery Jagiellonian, University Medical College in Cracow

author

Beata Tobiasz-Adamczyk

• Chair of Epidemiology and Preventive Medicine, Collegium Medicum Jagiellonian University in Cracow

author

Piotr Brzyski

• Chair of Epidemiology and Preventive Medicine, Collegium Medicum Jagiellonian University in Cracow

author

Jerzy Sałówka

• 3rd Department of General Surgery Jagiellonian, University Medical College in Cracow

author

Dagmara Kuliś

• Quality of Life Department, European Organization for Research and Treatment of Cancer

author

Piotr Richter

• 3rd Department of General Surgery Jagiellonian, University Medical College in Cracow

References

• Ponczek D, Nowicki A: Rak odbytnicy a jakość życia po operacji. Współcz Onkol 2004; 8: 153-59.
• Ponczek D, Nowicki A, Zegarski W et al.: Ocena jakości życia chorych leczonych chirurgicznie z powodu raka odbytnicy w aspekcie czynników społeczno-demograficznych. Współcz Onkol 2006; 10: 164-70.
• Pietrzak L, Bujko K, Nowacki MP et al., on behalf of the Polish Colorectal Study Group. Quality of life, anorectal and sexual functions after preoperative radiotherapy for rectal cancer: report of a randomized trial. Radiother Oncol 2007; 84: 217-25.[Crossref]
• Zając O, Spychała A, Murawa D et al.: Quality of assessment in patients with a stoma due to rectal cancer. Rep Pract Oncol Radiother 2008; 13: 130-34.[Crossref]
• Hendren SK, O'Connor BI, Liu M et al.: Prevalence of Male and Female Sexual Dysfunction Is High Following Surgery for Rectal Cancer. Ann Surg 2005; 242: 212-23.[Crossref]
• Fenech DS, Takahashi T, Liu M et al.: Function and quality of life after transanal excision of recital polyps and cancers. Dis Colon Rectum 2007; 50: 598-603.[WoS][Crossref]
• Banaszkiewicz Z, Szewczyk MT, Cieżniakowska K i wsp.: Jakość życia osób ze stomią jelitową. Współcz Onkol 2007; 11: 17-25.
• Zolciak A, Bujko K, Kepka L et al.: Abdominoperineal resection or anterior resection for rectal cancer: patients preferences before and after treatment. Colorectal Diseases 2006; 8: 575-80.
• Aaronson NK, Ahmedzal S, Bergman B et al.: The European Organisation for Research and Treatment of Cancer QLQ-C30: a quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993; 85: 365-76.[Crossref]
• Krzakowski M, Bujko K, Drosik K i wsp.: Systemowe leczenie raka okrężnicy i raka odbytnicy - uzgodnienia oparte na wynikach klinicznych badań. Onkologia w praktyce klinicznej 2007; 3: 267-85.
• Boehmer S, Luszczyńska A, Schwarzer R: Coping and quality of life after tumor surgery: Personal and social resources promote different domains of quality of life. Anxiety, Stress and Coping 2007; 20: 61-75.
• Gujral S, Conroy T, Fleissner C et al., on behalf of the European Organisation for Research and Treatment of Cancer Quality of Life Group: Assessing quality of life in patients with colorectal cancer: An update of the EORTC quality of life questionnaire. Eur J Cancer 2007; 43: 1564-73.[Crossref]
• Sprangers MAG, te Velde A, Aaronson NK, on behalf of the European Organisation for Research and Treatment of Cancer Study Group on Quality of life: The construction and testing of the EORTC colorectal cancer-speci?c quality of life questionnaire module (QLQ-CR38). Eur J Cancer 1999; 35: 238-47.[WoS][Crossref]
• Ponczek D, Nowicki A, Zegarski W, Banaszkiewicz Z: Ocena jakości życia chorych leczonych z powodu raka odbytnicy metodą resekcji przedniej niskiej lub wycięcia brzuszno-kroczowego, bez radioterapii przedoperacyjnej. Współcz Onkol 2005, 8, 359-64.
• Whistance RN, Conroy T, Chie W et al., on behalf of the European Organisation for the Research and Treatment of Cancer (EORTC) Quality of Life Group: Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer. Eur J Cancer 2009; 45: 3017-26.[WoS]
• Dewolf L, Koller M, Velikova G et al., on behalf of the EORTC Quality of Life Group.: EORTC Quality Of Life Group Translation Procedure, Third Edition. EORTC March 2009.
• Brzyski P: Trafność i rzetelność skal pomiarowych. W: Kawecka-Jaszcz K, Klocek M, Tobiasz-Adamczyk B (red.) Jakość życia w chorobach układu sercowo-naczyniowego. Metody pomiaru i znaczenie kliniczne. Termedia Wydawnictwo Medyczne, Poznań 2006, s. 43-54.
• Fayers PM, Machin D: Quality of life: assessment, analysis and interpretation. Chichester, New York, Weinheim, Brisbane, Singapore, Toronto: John Wiley & Sons Ltd.; 2000.
• Brzeziński J: Metodologia badań psychologicznych. Wydawnictwo Naukowe PWN, Warszawa 2006.

Identifiers

DOI

10.2478/v10035-011-0078-5