Technical and Immunological Aspects of Face Transplantation

• Authors: Maria Siemionow , Erhan Sonmez , Aleksandra Klimczak
• Languages of publication: EN

Abstracts

EN

The interest in facial transplantation led to development of many experimental models and novel immunosuppressive protocols. These studies allowed testing the immunological response to immunosuppressive protocols, and tolerance induction studies with supportive cell based therapies in composite tissues allograft transplants.In this article we present our experience with face transplantation models developed in our laboratory. We also summarize immunological responses and different immunosuppressive protocols used for tolerance induction through donor chimerism.

Keywords

EN

face transplantation; composite tissue allotransplantation; experimental models; cell therapy; skin rejection; tolerance induction; chimerism; immunosuppression; bone marrow transplantation

• Publisher: Index Copernicus International
• Journal: Polish Journal of Surgery
• Year: 2009
• Volume: 81
• Issue: 1
• Pages: 68-74

Dates

published

1 - 1 - 2009

online

20 - 3 - 2009

Contributors

author

Maria Siemionow

• Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA

author

Erhan Sonmez

• Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA

author

Aleksandra Klimczak

• Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA

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Identifiers

DOI

10.2478/v10035-009-0009-x