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2007 | 79 | 9 | 576-580

Article title

Deep Hypothermic Circulatory Arrest During Pulmonary Thrombendarterectomy in Patients with Chronic Thrombembolic Pulmonary Hypertension

Content

Title variants

Languages of publication

EN

Abstracts

EN
Chronic thrombembolic pulmonary hypertension is a rare complication of acute pulmonary embolism. Narrowing or closure of pulmonary arteries is the cause of pulmonary hypertension and results in right ventricular overload and failure. The treatment of choice is pulmonary thrombendarterectomy. Deep hypothermic circulatory arrest is a very important factor required for complete removal of the thrombembolic material from the pulmonary arteries during the operation.The aim of the study was the evaluation of the effectiveness of the use of deep hypothermic circulatory arrest during pulmonary thrombendarterectomy in patients with chronic thrombembolic pulmonary hypertension.Material and methods. Between October 1995 and October 2006 seventy patients were operated on. All of them were operated on with the use of deep hypothermic circulatory arrest. Deep hypothermia (18-19°C), pharmacotherapy, and neuromonitoring were used as a protection of the central nervous system during circulatory arrest.Results. In fifty-seven patients out of seventy, complete thrombendarterectomy was performed (more than 75% of branches opened). The average pulmonary artery pressure and pulmonary vascular resistance were decreased, and cardiac output and index were increased. Six patients died (8.6%).Conclusions. Complete thrombendarterectomy gives significant hemodynamical improvement in patients undergoing the operation. Deep hypothermic circulatory arrest during the operation does not cause significant neurological complications. Incomplete thrombendarterectomy may be the cause of right ventricular failure and death after the operation.

Year

Volume

79

Issue

9

Pages

576-580

Physical description

Dates

published
1 - 9 - 2007
online
11 - 2 - 2008

Contributors

author
  • Department of Cardiac Surgery, Institute of Cardiology, Warsaw
author
  • Department of Anaesthesiology, Institute of Cardiology, Warsaw
  • Department of Anaesthesiology, Institute of Cardiology, Warsaw
  • Department of Cardiac Surgery, Institute of Cardiology, Warsaw
  • Department of Cardiac Surgery, Institute of Cardiology, Warsaw

References

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  • Dartevelle P, Fadel E, Mussot S et al.: Chronic thromboembolic pulmonary hepertension. Eur Respir J 2004; 23: 637-48.[Crossref]
  • Jamieson SW, Kapelanski DP, Sakakibara N et al.: Pulmonary endarterectomy: experience and lessons learned in 1500 cases. Ann Thorac Surg 2003; 76: 1457-64.[Crossref][PubMed]
  • Biederman A, Dyk W, Torbicki A et al.: Trombendarterektomia tętnic płucnych w leczeniu w leczeniu chorych z nadciśnieniem płucnym w przebiegu przewlekłej zatorowości płucnej. Pol Arch Med Wew 2000; CIV, 5 (11).
  • Ogino H, Ando M, Matsuda H et al.: Japanese single-center experience of surgery for chronic thrombembolic pulmonary hypertension. Ann Thorac Surg 2006; 82: 630-36.[Crossref]
  • Puis L, Vandezande E, Vercaemst L et al.: Pulmonary thrombendarterectomy for chronic thrombembolic pulmonary hypertension. Perfusion 2005; 20: 101-08.[Crossref]
  • Manecke GR, Wilson WC, Auger WR et al.: Chronic thrombembolic pulmonary hypertension and Pulmonary Thrombendarterectomy. Seminars in Cardiotho and Vasc Anesth 2005; 9(3): pp189-204.
  • Heinrich M, Uder M, Tscholl D et al.: CT Scan Findings in Chronic Thrombembolic Pulmonary Hypertension. Predictors of Hemodynamic Improvement After Pulmonary Thrombendarterectomy. Chest 2005; 127: 1606-13.[Crossref]
  • Auger WR, Ker KM, Kim NHS et al.: Chronic thrombembolic Pulmonary Hypertension. Cardiol Clin 2004; 22: 453-66.[Crossref]
  • Mellemkjaer S, Ilkjaer LB, Klaaborg KE et al.: Pulmonary endarterectomy for chronic thrombembolic pulmonary hypertension. Ten years experience in Denmark. Scand Cardiovasc J 2006; 40: 49-53.[Crossref]
  • Hagl C, Khaladj N, Peters T et al.: Technical advances of pulmonary thrombemboendarterectomy for chronic Thromboembolic pulmonary hypertension. Eur J Cardio-thoracic Surg 2003; 23: 776-81.
  • Duebner LF: Effects of ph management during deep hypothermic by-pass on cerebral circulation. Circulation 2002; 106: 1-103.
  • Edmonds H: Multi-modality neurophysiologic monitoring for cardiac surgery. Heart Surg Forum 2002; 5: 225-28.[PubMed]
  • Edmonds H: Protective effect of neuromonitoring during cardiac surgery. Ann N Y Acad Sci 2005; 1053: 12-19.

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_v10035-007-0090-y
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