Splenectomy in Patients with Hematological Disorders - Our Experience

• Authors: Piotr Żukrowski , Wojciech Kielan , Zygmunt Grzebieniak , Jerzy Rudnicki , Robert Tarnawa , Anil Agrawal , Tomasz Bąk , Monika Knakiewicz
• Languages of publication: EN

Abstracts

EN

The aim of the study. Retrospective analysis of indications for splenectomy in hematological diseases, positive effect of this operation and correlations between objective prognostic factors and good response to splenectomy in patients with different hematological indications for splenectomy.Material and methods. 98 adult patients with hematological disorders, who were splenectomised in the years 1994 - 2004. We evaluated the effects of splenectomy in patients with hematological diseases as defined by patient documentation from the 2nd Department of General and Oncological Surgery, Department of Hematology and Hematological Ambulance and the questionnaires that patients completed by themselves.Results. The beneficial effect of splenectomy was observed in the majority of cases of idiopathic thrombocytopenic purpura (41 of 53 patients), acquired hemolytic anemia (2 of 3 patients) and hereditary spherocytosis (8 of 9 patients). Surgery can provide a high frequency of durable response for adult patients with benign hematological disorders. In malignant hematological diseases, splenectomy eliminates consequences of hypersplenism or splenomegaly. Splenectomy in patients with malignant hematological disorders can improve their condition and relieve symptoms of hypersplenism and splenomegaly to improve their quality of life. There were early complications in 11 patients (11.3%). Mortality was 2%. Late complications appeared in 24 patients out of 96 patients, who survived the perioperative period. The most common late complication was moderate respiratory infections.Conclusions. Splenectomy is the most common operation in patients with hematological disorders. Indications for splenectomy have been hindered by the lack of any objective prognostic factors of good postoperative response. Nevertheless, the effect of splenectomy is positive in many patients with benign and malignant hematological diseases.

Keywords

EN

splenectomy; hematological disease

• Publisher: Index Copernicus International
• Journal: Polish Journal of Surgery
• Year: 2007
• Volume: 79
• Issue: 6
• Pages: 426-435

Dates

published

1 - 6 - 2007

online

27 - 11 - 2007

Contributors

author

Piotr Żukrowski

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Wojciech Kielan

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Zygmunt Grzebieniak

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Jerzy Rudnicki

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Robert Tarnawa

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Anil Agrawal

author

Tomasz Bąk

• Department of General and Oncological Surgery, Medical University, Wrocław

author

Monika Knakiewicz

• Department of General and Oncological Surgery, Medical University, Wrocław

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Identifiers

DOI

10.2478/v10035-007-0066-y