LiOH.H2O as a catalyst for Knoevenagel and Gewald reactions

• Authors: Moustafa Gouda
• Languages of publication: EN

Abstracts

EN

Commercial available lithium hydroxide monohydrate LiOH.H2O was found to be a novel ‘dual activation’ catalyst for tandem cross Knoevenagel condensation between malononitrile or ethylcyanoacetate and aromatic aldehydes leading to an efficient and easy synthesis of the corresponding arylidenes at room temperature in a short reaction time. In the case of salicyaldehyde the reaction lead to the formation of 3-substituted coumarins. The high efficacy, cheapness and easy availability of LiOH.H2O prompted us to investigate its validity as a basic catalyst for Gewald reaction.

Keywords

EN

Malononitrile; Ethylcyanoacetate; Cyclohexanone; LiOH.H2O; Knoevenagel reaction; Gewald reaction

• Publisher: De Gruyter Open
• Journal: Polish Journal of Chemical Technology
• Year: 2010
• Volume: 12
• Issue: 4
• Pages: 31-35

Dates

published

1 - 1 - 2010

online

28 - 12 - 2010

Contributors

author

Moustafa Gouda

• Chemistry Department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt

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Identifiers

DOI

10.2478/v10026-010-0046-6