In vitro tests of dense hydroxyapatite materials

• Authors: Agnieszka Sobczak , Anna Kida , Zygmunt Kowalski , Zbigniew Wzorek
• Languages of publication: EN

Abstracts

EN

The paper presents the results of the calcining process of deproteinised and defatted bone pulp called bone sludge. The calcining process was performed in two stages. The first step of the calcining process was realized at the temperature of 600°C in a rotary kiln. In the second stage the obtained bone ashes were calcined at five different temperatures from 650°C to 950°C for 2 hours in a chamber kiln and in air atmosphere. The products of the calcining process were characterized by the XRD method. Calcium content was determined by titration whereas the contents of total phosphorus and acid-soluble phosphorus - by the spectrophotometric method. The X-ray analysis confirmed that hydroxyapatite is the main component of the calcining products. Calcium and phosphorus contents were kept at the level of 40% and 17.5%, respectively, which corresponded to the Ca/P ratio of not stechiometric hydroxyapatite. In vitro studies, in the simulated body fluid, Ringer liquid and distilled water were realised. The measurements of pH value of SBF and Ringer fluid were realized. Additionally electrical conductivity as well as pH for distilled water where conducted. The goal of these tests was to evaluate chemical durability of dense hydroxyapatite materials.

Keywords

EN

hydroxyapatite; dense materials; in vitro tests; incubation

• Publisher: De Gruyter Open
• Journal: Polish Journal of Chemical Technology
• Year: 2009
• Volume: 11
• Issue: 1
• Pages: 44-49

Dates

published

1 - 1 - 2009

online

6 - 4 - 2009

Contributors

author

Agnieszka Sobczak

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, ul. Warszawska 24, 31-155 Kraków, Poland

author

Anna Kida

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, ul. Warszawska 24, 31-155 Kraków, Poland

author

Zygmunt Kowalski

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, ul. Warszawska 24, 31-155 Kraków, Poland

author

Zbigniew Wzorek

• Institute of Inorganic Chemistry and Technology, Cracow University of Technology, ul. Warszawska 24, 31-155 Kraków, Poland

References

• Ślósarczyk, A., Stobierska, E. & Paszkiewicz, Z. (1994). Hydroxyapatite as an implantological material Ceramics 46 Polish Ceramic Bulletin (in Polish).
• Knychalska-Karwan, Z. & Ślósarczyk, A. (1994). Hydroxyapatite in stomatology Krakmedia, Kraków (in Polish).
• Ślósarczyk, A. (1997). Hydroxyapatite bioceramics Biuletyn Ceramiczny nr 13 Ceramika 51, Polskie Towarzystwo Ceramiczne, Kraków (in Polish).
• Shin, H., Jo, S. & Mikos, A.G. (2003). Biomimetic materials for tissue engineering. Biomaterials 24, 4353 - 4364.[PubMed][Crossref]
• Vallet-Regi, M. & Gonzales-Calbert J. (2004). Calcium phosphates as substitution of bone tissues. Prog. Solid St. Chem. 32, 1 - 31. Received 1 December 2003; received in revised form 1 June 2004; accepted 15 July 2004, from Science Direct database on the World Wide Web: www.elsevier.nl/locate/pssc. DOI:10.1016/j.progsolidstchem.2004.07.001. [Crossref]
• Kokubo, T. & Takadama, H. (2006). How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27, 2907 - 2915. Received 6 September 2005; accepted 13 January 2006 Available online 31 January 2006from Science Direct database on the World Wide Web: www.elsevier.com/locate/biomaterials. DOI:10.1016/j.biomaterials.2006.01.017. [Crossref]

Identifiers

DOI

10.2478/v10026-009-0011-4