Modeling of the influence of the modifier concentration on the retention process in NP-HPLC

• Authors: Wojciech Zapała
• Languages of publication: EN

Abstracts

EN

The adsorption model for an accurate prediction of the analyte retention in the normal - phase liquid chromatography with a binary mobile phase has been proposed. This model was derived using a thermody-namically consistent modified competitive Langmuir isotherm. The performance of the proposed equation was compared with two retention models reported in literature. All models were verified for different NP-LC systems by use of three criteria: the sum of squared differences between the experimental and theoretical data, approximation of the standard deviation and the Fisher test.

Keywords

EN

NP-HPLC; retention models; mobile phase composition

• Publisher: De Gruyter Open
• Journal: Polish Journal of Chemical Technology
• Year: 2008
• Volume: 10
• Issue: 1
• Pages: 52-56

Dates

published

1 - 1 - 2008

online

3 - 4 - 2008

Contributors

author

Wojciech Zapała

• Department of Chemical and Process Engineering, Chemical Faculty, Rzeszów University of Technology, Powstańców Warszawy 6, 35-959 Rzeszów, Poland

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Identifiers

DOI

10.2478/v10026-008-0013-7