Establishment of in vitro 192Ir γ-ray dose-response relationship for dose assessment by the lymphocyte dicentric assay

• Authors: Maria Kowalska , Katarzyna Meronka , Kamil Szewczak
• Languages of publication: EN

Abstracts

EN

In vitro dose-response relationships are used to describe the relation between dicentric chromosomes and radiation dose for human peripheral blood lymphocytes. The dicentric yield depends on both the dose and the radiation quality. Thus, for reliable dose estimation in vitro dose responses must be determined for different radiation qualities. This paper reports the work for setting up the relationship for the dicentric production in the lymphocytes exposed in vitro to 192Ir g-rays at Central Laboratory for Radiological Protection (CLOR). In a case of a radiation accident in industrial radiography using 192Ir sealed sources, this will be the basis for the indirect evaluation of the g-ray dose to which an accidental victim was exposed.

Keywords

EN

biodosimetry; cytogenetic analysis; radiation exposure

• Publisher: Versita
• Journal: Polish Journal of Medical Physics And Engineering
• Year: 2012
• Volume: 18
• Issue: 1
• Pages: 11-21

Dates

published

1 - 03 - 2012

online

26 - 02 - 2013

Contributors

author

Maria Kowalska

• Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland

author

Katarzyna Meronka

• Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland

author

Kamil Szewczak

• Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland

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Identifiers

DOI

10.2478/v10013-012-0003-1