Changes in the cardiac muscle electric activity as a result of Coronary Artery Bypass Graft operation

• Authors: Magdalena Grajek , Ryszard Krzyminiewski , Ryszard Kalawski , Mariusz Kulczak
• Languages of publication: EN

Abstracts

EN

Many bioelectric signals have a complex internal structure that can be a rich source of information on the tissue or cell processes. The structure of such signals can be analysed in detail by applying digital methods of signal processing. Therefore, of substantial use in diagnosis of the coronary arterial disease is the method of digital enhancement of increasing signal resolution ECG (NURSE-ECG), permitting detection of temporary changes in the electric potentials in the cardiac muscle in the process of depolarisation. Thanks to the application of NURSE-ECG it has become possible to detect relatively small changes in the electric activity of particular fragments of the cardiac muscle undetectable by the standard ECG method, caused by ischemia, the effect of a drug or infarct.The aim of this study was to identify and analyse changes in the electric activity of the cardiac muscle as a result of the Coronary Artery Bypass Graft (CABG) operation. In this study the method of NURSE-ECG has been applied in order to identify and analyse changes in the electric activity of the cardiac muscle as a result of the CABG operation. In the study performed in cooperation of the Institute of Physics Adam Mickiewicz University and the Strus Hospital, Cardiac Surgery Ward, 37 patients with advanced coronary arterial disease were asked to participate. The patients were examined prior to the operation, on the day after the operation and two months after the operation and a year after the operation. The ECG recordings were subjected to a numerical procedure of resolution enhancement by a NURSE-ECG program to reveal the tentative changes in the electric potential of the cardiac muscle on its depolarisation. Results of the study have shown that the NURSE ECG method can be applied to monitor changes in the electric activity of the cardiac muscle occurring as a result of CABG operation. One the second day after the operation in the majority of patients (70%) a rapid decrease of the total cardiac muscle activity was observed. The NURSE ECG seems to be a promising supplementary method in medical diagnosis. In particular it can be applied for qualification of patients for CABG operation and for verification of the operation effects.

Keywords

EN

coronary artery bypass graft; depolarization; numerical sygnal resolution enhancement electrocardiography; NURSE-ECG

• Publisher: Versita
• Journal: Polish Journal of Medical Physics And Engineering
• Year: 2008
• Volume: 14
• Issue: 4
• Pages: 227-249

Dates

published

1 - 1 - 2008

online

14 - 4 - 2009

Contributors

author

Magdalena Grajek

• Institute of Physics, A. Mickiewicz University, Umultowska 85,61-614 Poznan, Poland

author

Ryszard Krzyminiewski

• Cardiac Surgery Ward, Strus Hospital, Poznan, Poland

author

Ryszard Kalawski

• Cardiac Surgery Ward, Strus Hospital, Poznan, Poland

author

Mariusz Kulczak

• Cardiac Surgery Ward, Strus Hospital, Poznan, Poland

References

• Dunn M, Lipman BS, Massie E. Clinical Electrocardiography. Year Book Medical Publishers Inc. Chicago 1984.
• Krzyminiewski R, Ozegowski S, Poprawski K, Wierzchowiecki M. New diagnostic possibbilities offered by reading electrocardiographic signals of enhanced resolution of the QRS complex. Physica Medica. 1997; XIII(1): 326.
• Krzyminiewski R, Panek G, Piszczek I, Stepien A, Stepien R. High-resolution Vectorcardiograms in the Diagnosis of Myocardial Ischaemia. Pol J Med Phys Eng. 1999; 5(1): 1-9.
• Krzyminiewski R. Computer enhancement of complex spectroscopic spectra resolution. Mol Phys Reports. 1994; 6: 174.
• Atherton NM, Crossland WA, A single-crystal ENDOR study of g-irradiated pyridoxine hydrochloride. J Chem Soc Faraday Trans. I 1987; 83: 37-42.[Crossref]
• Karolinska Institute
• Krzyminiewski R, Panek G, Stepien R. High resolution vectorcardiogram. J Med Phys. 1999; 24: 181-185.
• Lauer M, Martino D. Quantitative Measures of Electrocardiographic Left Ventricular Mass, Conducion, and Repolarization, and Long-Term Survival After Coronary Artery Bypass Grafting. Circulation. 2007; 116: 888-893.[WoS][Crossref]
• Krzyminiewski R. Computer enhancement of complex spectroscopic spectra resolution. Mol Phys Reports. 1994; 6: 174.
• Krzyminiewski R. Proc. XV Conf. Radio and Microwave Spectroscopy Ramis'93. 1993; 36.
• Kulick D, Shiel WC Jr. Coronary Artery Bypass Graft Surgery (CABG) [Internet]. New York: WebMD; c1999-2008 [cited: 2008]. Available from: http://www.medicinenet.com/coronary_artery_bypass_graft/page1.htm
• Krzyminiewski R, Panek G, Stepien R. Corelation of results of coronarographic, SPECT examination and high-resolution vectorcardiography. Proceedings of the European Medical and Biological Engineering Conference EMBEC'99. 1999; 514-515.
• Medrado GA, Micheli AA. [Electrocardiogram and vectocardiograma in infarct of the myocardium]. La Prensa Medica Mexicana. Mexico 1971. Spanish.

Identifiers

DOI

10.2478/v10013-008-0019-8