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Journal

2014 | 9 | 5 | 653-656

Article title

Sertoli-Leydig tumor and male pseudohermaphroditism discovered during inguinal hernia surgery

Content

Title variants

Languages of publication

EN

Abstracts

EN
The diagnosis of inguinal hernia is usually clinical and it is performed with high sensitivity and specificity. Very occasionally, it may be confused with other diseases (lymphadenopathy, testicular pathology,etc). We report a rare case of a 80-year-old woman with a clinical diagnosis of hernia, which was underwent surgery and a tumor from the hernia orifice was found. After histological analysis we discovered that the misdiagnosed hernia was actually a tumor on a rudimentary testis. After radiological, gynecological and cytogenetic assessment we obtained an unexpected diagnosis: Male psheudohermaphroditism and Sertoli-Leydigtumor (SLCT) development on the testis. Diagnostic guidance for disorders of sexual development is based almost entirely on pediatric experience and very few guidelines are available for adults. Male pseudohermaphroditism is an intersex condition in which the carriers show a phenotype that includes external female genitalia, but a male genetic and gonadal sex. SLCT are sex-cord stromal tumors which develop in ovary and very rarely in the testis, representing 0.1–0.5% of ovarian tumors and less than 0.2% of testicular tumors. Thus far 24 case have been reported in the literature in which SLCT tumor has developed on testis.

Publisher

Journal

Year

Volume

9

Issue

5

Pages

653-656

Physical description

Dates

published
1 - 10 - 2014
online
31 - 7 - 2014

Contributors

  • Department of Digestive and General Surgery, Hospital General de l’Hospitalet, Catalonia, Spain
author
  • Department of Digestive and General Surgery, Hospital General de l’Hospitalet, Catalonia, Spain
author
  • Department of Digestive and General Surgery, Hospital General de l’Hospitalet, Catalonia, Spain
author
  • Department of Radiology, Hospital General de l’Hospitalet, Catalonia, Spain
author
  • Department of Pahtology, Hospital General de l’Hospitalet, Catalonia, Spain
author
  • Department of Pahtology, Hospital General de l’Hospitalet, Catalonia, Spain

References

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  • [2] Liao X, Liang D, Li Y, et al. Mutation analysis of the SRY, NR5A1 and DHH genes in six Chinese 46. XY women. J MaternFetalNeonaltal Med 2011;24(6):863–866
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  • [7] Rutger JKL. The case reported as bilateral Sertoli-Leydig cell tumor in a 61-year old woman with uterine apalasia may instead represent complete androgen insensitivity syndrome. Int J GynecolPathol 2011;30:395 [Crossref]
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  • [12] Pérez-Becerra R, Santana-Ríos Z, Hulda-Graus S, et al. Tumores del Estroma Gonadal Sertoli-Leydig en el Hospital General Dr Manuel GeaGonzález. Rev MexUrol 2009;69(3):174–177
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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-013-0317-8
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