Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results

Journal

2014 | 9 | 2 | 306-312

Article title

FDG-PET-CT in the early response evaluation for primary systemic therapy of breast cancer

Content

Title variants

Languages of publication

EN

Abstracts

EN
Primary systemic therapy (PST) is a standard treatment for patients with locally advanced breast cancer. We report one of our patients to demonstrate the optimal use of FDG-PET-CT in the routine clinical workup during PST, especially when clinicians face contradictory clinical and pathological findings, and to show the advantages of this imaging modality in the decision-making process about the initial treatment choice. By reviewing the literature we would also like to confirm that FDG-PET-CT is highly sensitive in the measurement of the early therapeutic response and the prediction of the complete pathological remission, as early as after the first cycle of chemotherapy is administered.

Publisher

Journal

Year

Volume

9

Issue

2

Pages

306-312

Physical description

Dates

published
1 - 4 - 2014
online
13 - 2 - 2014

Contributors

  • 1st Department of Internal Medicine, Oncology Division Semmelweis University, Hungary, Budapest, 1083, Tömő u. 25-29
  • 1st Department of Internal Medicine, Oncology Division Semmelweis University, Hungary, Budapest, 1083, Tömő u. 25-29
author
  • 2nd Department of Pathology, Semmelweis University, Hungary, Budapest, 1091, Üllői út 93
author
  • 2nd Department of Pathology, Semmelweis University, Hungary, Budapest, 1091, Üllői út 93
author
  • 2nd Department of Pathology, Semmelweis University, Hungary, Budapest, 1091, Üllői út 93
author
  • 1st Department of Internal Medicine, Oncology Division Semmelweis University, Hungary, Budapest, 1083, Tömő u. 25-29
  • 1st Department of Surgery, Semmelweis University, Hungary, Budapest, 1082, Üllői út 78
author
  • Pozitron Diagnostics Ltd. Budapest, Hungary, Budapest, 1117, Hunyadi J. út 9
author
  • 1st Department of Internal Medicine, Oncology Division Semmelweis University, Hungary, Budapest, 1083, Tömő u. 25-29

References

  • [1] Kaufmann M, von Minckwitz G, Smith R, Valero V, Gianni L, Eiermann W et al. International expert panel on the use of primary (preoperative) systemic treatment of operable breast cancer: review and recommendations. J Clin Oncol, 2003, 21, 2600–2608 http://dx.doi.org/10.1200/JCO.2003.01.136[Crossref]
  • [2] Kaufmann M, Hortobagyi GN, Goldhirsch A, Scholl S, Makris A, Valagussa P et al. Recommendations from an international expert panel on the use of neoadjuvant (primary) systemic treatment of operable breast cancer: an update. J Clin Oncol, 2006, 24, 1940–1949 http://dx.doi.org/10.1200/JCO.2005.02.6187[Crossref]
  • [3] Bonadonna G, Veronesi U, Brambilla C, Ferrari L, Luini A, Greco M et al. Primary chemotherapy to avoid mastectomy in tumors with diameters of three centimeters or more. J Natl Cancer Inst, 1990, 82, 1539–1545 http://dx.doi.org/10.1093/jnci/82.19.1539[Crossref]
  • [4] Kulka J, Tokes AM, Toth AI, Szasz AM, Farkas A, Borka K et al. [Immunohistochemical phenotype of breast carcinomas predicts the effectiveness of primary systemic therapy]. Magy Onkol, 2009, 53, 335–343 http://dx.doi.org/10.1556/MOnkol.53.2009.4.2[Crossref]
  • [5] Fisher B, Bryant J, Wolmark N, Mamounas E, Brown A, Fisher ER et al. Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol, 1998, 16, 2672–2685
  • [6] Fisher B, Brown A, Mamounas E, Wieand S, Robidoux A, Margolese RG et al. Effect of preoperative chemotherapy on local-regional disease in women with operable breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-18. J Clin Oncol, 1997, 15, 2483–2493
  • [7] Wolff AC, Davidson NE. Preoperative therapy in breast cancer: lessons from the treatment of locally advanced disease. Oncologist, 2002, 7, 239–245 http://dx.doi.org/10.1634/theoncologist.7-3-239[Crossref]
  • [8] Sachelarie I, Grossbard ML, Chadha M, Feldman S, Ghesani M, Blum RH. Primary systemic therapy of breast cancer. Oncologist, 2006, 11, 574–589 http://dx.doi.org/10.1634/theoncologist.11-6-574[Crossref]
  • [9] Tardivon AA, Ollivier L, El Khoury C, Thibault F. Monitoring therapeutic efficacy in breast carcinomas. Eur Radiol, 2006, 16, 2549–2558 http://dx.doi.org/10.1007/s00330-006-0317-z[Crossref]
  • [10] Schelling M, Avril N, Nahrig J, Kuhn W, Romer W, Sattler D et al. Positron emission tomography using [(18)F]Fluorodeoxyglucose for monitoring primary chemotherapy in breast cancer. J Clin Oncol, 2000, 18, 1689–1695
  • [11] Smith IC, Welch AE, Hutcheon AW, Miller ID, Payne S, Chilcott F et al. Positron emission tomography using [(18)F]-fluorodeoxy-D-glucose to predict the pathologic response of breast cancer to primary chemotherapy. J Clin Oncol, 2000, 18, 1676–1688
  • [12] Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer, 2009, 45, 228–247 http://dx.doi.org/10.1016/j.ejca.2008.10.026[Crossref]
  • [13] Forrai G, Szabo E, Ormandi K, Ambrozay E, Pentek Z, Milics M et al. [Imaging methods in the current diagnosis of and screening for breast cancer]. Magy Onkol, 2010, 54, 211–216 http://dx.doi.org/10.1556/MOnkol.54.2010.3.2[Crossref]
  • [14] Wahl RL, Zasadny K, Helvie M, Hutchins GD, Weber B, Cody R. Metabolic monitoring of breast cancer chemohormonotherapy using positron emission tomography: initial evaluation. J Clin Oncol, 1993, 11, 2101–2111
  • [15] Lee JH, Rosen EL, Mankoff DA. The role of radiotracer imaging in the diagnosis and management of patients with breast cancer: part 2-response to therapy, other indications, and future directions. J Nucl Med, 2009, 50, 738–748 http://dx.doi.org/10.2967/jnumed.108.061416[WoS]
  • [16] Wang Y, Zhang C, Liu J, Huang G. Is 18F-FDG PET accurate to predict neoadjuvant therapy response in breast cancer? A meta-analysis. Breast Cancer Res Treat, 2012, 131, 357–369 http://dx.doi.org/10.1007/s10549-011-1780-z[Crossref][WoS]
  • [17] Rousseau C, Devillers A, Sagan C, Ferrer L, Bridji B, Campion L et al. Monitoring of early response to neoadjuvant chemotherapy in stage II and III breast cancer by [18F]fluorodeoxyglucose positron emission tomography. J Clin Oncol, 2006, 24, 5366–5372 http://dx.doi.org/10.1200/JCO.2006.05.7406[Crossref]
  • [18] Berriolo-Riedinger A, Touzery C, Riedinger JM, Toubeau M, Coudert B, Arnould L et al. [18F]FDGPET predicts complete pathological response of breast cancer to neoadjuvant chemotherapy. Eur J Nucl Med Mol Imaging, 2007, 34, 1915–1924 http://dx.doi.org/10.1007/s00259-007-0459-5[Crossref]
  • [19] Ueda S, Tsuda H, Saeki T, Omata J, Osaki A, Shigekawa T et al. Early metabolic response to neoadjuvant letrozole, measured by FDG PET/CT, is correlated with a decrease in the Ki67 labeling index in patients with hormone receptor-positive primary breast cancer: a pilot study. Breast Cancer, 2011, 18, 299–308 http://dx.doi.org/10.1007/s12282-010-0212-y[Crossref][WoS]
  • [20] Schwarz-Dose J, Untch M, Tiling R, Sassen S, Mahner S, Kahlert S et al. Monitoring primary systemic therapy of large and locally advanced breast cancer by using sequential positron emission tomography imaging with [18F]fluorodeoxyglucose. J Clin Oncol, 2009, 27, 535–541 http://dx.doi.org/10.1200/JCO.2008.17.2650[Crossref][WoS]
  • [21] Keam B, Im SA, Koh Y, Han SW, Oh DY, Cho N et al. Early metabolic response using FDG PET/CT and molecular phenotypes of breast cancer treated with neoadjuvant chemotherapy. BMC cancer, 2011, 11, 452 http://dx.doi.org/10.1186/1471-2407-11-452[WoS][Crossref]
  • [22] Kolesnikov-Gauthier H, Vanlemmens L, Baranzelli MC, Vennin P, Servent V, Fournier C et al. Predictive value of neoadjuvant chemotherapy failure in breast cancer using FDG-PET after the first course. Breast Cancer Res Treat, 2012, 131, 517–525 http://dx.doi.org/10.1007/s10549-011-1832-4[Crossref]
  • [23] Groheux D, Giacchetti S, Espie M, Rubello D, Moretti JL, Hindie E. Early monitoring of response to neoadjuvant chemotherapy in breast cancer with 18F-FDG PET/CT: defining a clinical aim. Eur J Nucl Med Mol Imaging, 2011, 38, 419–425 http://dx.doi.org/10.1007/s00259-010-1660-5[Crossref]
  • [24] Buck A, Schirrmeister H, Kuhn T, Shen C, Kalker T, Kotzerke J et al. FDG uptake in breast cancer: correlation with biological and clinical prognostic parameters. Eur J Nucl Med Mol Imaging, 2002, 29, 1317–1323 http://dx.doi.org/10.1007/s00259-002-0880-8[Crossref][WoS]
  • [25] Buck AK, Schirrmeister H, Mattfeldt T, Reske SN. Biological characterisation of breast cancer by means of PET. Eur J Nucl Med Mol Imaging 2004, 31Suppl 1, S80–87 http://dx.doi.org/10.1007/s00259-004-1529-6[Crossref]
  • [26] Buban T, Toth L, Tanyi M, Kappelmayer J, Antal-Szalmas P. [Ki-67 - new faces of an old player]. Orv Hetil, 2009, 150, 1059–1070 http://dx.doi.org/10.1556/OH.2009.28638[Crossref]
  • [27] de Azambuja E, Cardoso F, de Castro G, Jr., Colozza M, Mano MS, Durbecq V et al. Ki-67 as prognostic marker in early breast cancer: a metaanalysis of published studies involving 12,155 patients. Br J Cancer, 2007, 96, 1504–1513 http://dx.doi.org/10.1038/sj.bjc.6603756[WoS][Crossref]
  • [28] Colozza M, Azambuja E, Cardoso F, Sotiriou C, Larsimont D, Piccart MJ. Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now? Ann Oncol, 2005, 16, 1723–1739 http://dx.doi.org/10.1093/annonc/mdi352[Crossref]
  • [29] Avril N, Menzel M, Dose J, Schelling M, Weber W, Janicke F et al. Glucose metabolism of breast cancer assessed by 18F-FDG PET: histologic and immunohistochemical tissue analysis. J Nucl Med, 2001, 42, 9–16
  • [30] Bos R, van Der Hoeven JJ, van Der Wall E, van Der Groep P, van Diest PJ, Comans EF et al. Biologic correlates of (18)fluorodeoxyglucose uptake in human breast cancer measured by positron emission tomography. J Clin Oncol, 2002, 20, 379–387 http://dx.doi.org/10.1200/JCO.20.2.379[Crossref]
  • [31] Shimoda W, Hayashi M, Murakami K, Oyama T, Sunagawa M. The relationship between FDG uptake in PET scans and biological behavior in breast cancer. Breast Cancer, 2007, 14, 260–268 http://dx.doi.org/10.2325/jbcs.14.260[Crossref]
  • [32] Gil-Rendo A, Martinez-Regueira F, Zornoza G, Garcia-Velloso MJ, Beorlegui C, Rodriguez-Spiteri N. Association between [18F]fluorodeoxyglucose uptake and prognostic parameters in breast cancer. Br J Surg, 2009, 96, 166–170 http://dx.doi.org/10.1002/bjs.6459[WoS][Crossref]
  • [33] Koolen BB, Vrancken Peeters MJ, Wesseling J, Lips EH, Vogel WV, Aukema TS et al. Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy. Eur J Nucl Med Mol Imaging, 2012, 39, 1830–1838 http://dx.doi.org/10.1007/s00259-012-2211-z[Crossref][WoS]
  • [34] Tchou J, Sonnad SS, Bergey MR, Basu S, Tomaszewski J, Alavi A et al. Degree of tumor FDG uptake correlates with proliferation index in triple negative breast cancer. Mol Imaging Biol, 2010, 12, 657–662 http://dx.doi.org/10.1007/s11307-009-0294-0[WoS][Crossref]
  • [35] Varga Z, Diebold J, Dommann-Scherrer C, Frick H, Kaup D, Noske A et al. How reliable is Ki-67 immunohistochemistry in grade 2 breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists. PloS one, 2012, 7, e37379 http://dx.doi.org/10.1371/journal.pone.0037379[WoS]
  • [36] Iqbal S, Anderson TJ, Marson LP, Prescott RJ, Dixon JM, Miller WR. MIB-1 assessments in breast cancers. Breast, 2002, 11, 252–256 http://dx.doi.org/10.1054/brst.2002.0408[Crossref]
  • [37] Berruti A, Generali D, Kaufmann M, Puztai L, Curigliano G, Aglietta M et al. International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010). Journal of the National Cancer Institute Monographs, 2011, 147–151

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-013-0268-0
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.