Thyroid dysfunction and cardiovascular risk factors in Bulgarian adults

• Authors: Alexander Shinkov , Anna-Maria Borissova , Roussanka Kovatcheva , Jordan Vlahov , Lilia Dakovska , Iliana Atanassova , Mirtcho Vukov , Nina Aslanova
• Languages of publication: EN

Abstracts

EN

The aim of this study was to determine the prevalence of thyroid dysfunction and its association with cardiovascular risk factors in an adult Bulgarian population. 2402 subjects were studied, 1347 female, 20–94y (median: 48.0y) and 1055 male, 20–91y (median: 45.5y). Body weight, height, waist circumference, arterial blood pressure, TSH, FT4 and lipids were measured. Known hypothyroidism was reported by 53 subjects (2.2%) and hyperthyroidism by 20 (0.8%). New hypothyroidism was found in 98 (4.1%), [subclinical (3.2%), overt (0.9%)]. New hyperthyroidism was found in 68 (2.9%), [subclinical (2.5%), overt (0.4%)]. New diagnosis of hypothyroidism and hyperthyroidism was entered in 84% and 87% in male subjects and 60% and 65% in the females respectively. Arterial hypertension was present in 40% of the women and in 47% of the men (p<0.001) and was more prevalent in hypothyroidism. Abdominal obesity and dyslipidemia were more prevalent in males and hypothyroid subjects. Arterial hypertension depended on age, gender and lipid status but not on thyroid function. CHD history depended on thyroid function and age. Conclusion: Most cases of thyroid dysfunction were undiagnosed, especially in the males. CV risk factors were more prevalent in the males with thyroid dysfunction a major determinant of CHD, but not hypertension.

Keywords

EN

Thyroid dysfunction; Hypothyroidism; Cardiovascular disease risk factors; Hypertension

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2013
• Volume: 8
• Issue: 6
• Pages: 742-748

Dates

published

1 - 12 - 2013

online

6 - 12 - 2013

Contributors

author

Alexander Shinkov

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Anna-Maria Borissova

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Roussanka Kovatcheva

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Jordan Vlahov

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Lilia Dakovska

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Iliana Atanassova

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

author

Mirtcho Vukov

• National Center for Medical Information, Sofia, Bulgaria

author

Nina Aslanova

• Clinical Center of Endocrinology, Medical University of Sofia, Sofia, Bulgaria

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Identifiers

DOI

10.2478/s11536-013-0235-9