Prenatal, perinatal and neonatal risk factors for autism - study in Poland

• Authors: Dorota Mrozek-Budzyn , Renata Majewska , Agnieszka Kieltyka
• Languages of publication: EN

Abstracts

EN

The results of conducted research studies suggest that heredity and early fetal and neonatal development play a causal role in autism. The objective was to determine a relationship between pre-, peri-, and neonatal factors and autism. The relationship between genders and individual risk factors for autism was also examined. A case-control study was conducted among 288 children (96 cases with childhood or atypical autism and 192 controls individually matched to cases by the year of birth, sex, and general practitioners). Data on autism diagnosis and other medical conditions were acquired from physicians. All other information on potential autism risk factors were collected from mothers. Autism risk was significantly higher when mothers were taking medications (OR=2.72, 95%CI: 1.47-5.04) and smoked during pregnancy (OR=3.32, 95%CI: 1.12-9.82). It was also significantly associated with neonatal dyspnea (OR=3.20, 95%CI: 1.29-8.01) and congenital anomalies (OR=7.17, 95%CI: 2.23-23.1). In gender analysis only congenital anomalies were significantly associated with autism for girls but all of mentioned factors stayed independent risk factors for boys.

Keywords

EN

Autism; Prenatal; Perinatal; Neonatal; Risk factors

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2013
• Volume: 8
• Issue: 4
• Pages: 424-430

Dates

published

1 - 8 - 2013

online

12 - 6 - 2013

Contributors

author

Dorota Mrozek-Budzyn

• Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Kopernika 7a, 31-034, Krakow, Poland

author

Renata Majewska

• Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Kopernika 7a, 31-034, Krakow, Poland

author

Agnieszka Kieltyka

• Chair of Epidemiology and Preventive Medicine, Jagiellonian University Medical College, Kopernika 7a, 31-034, Krakow, Poland

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Identifiers

DOI

10.2478/s11536-013-0174-5