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Journal

2013 | 8 | 2 | 237-243

Article title

Subcutaneous adipose tissue measurements and better metabolic prediction

Content

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EN

Abstracts

EN
The aim of the study was to establish the importance of an additional measurement of subcutaneous adipose tissue thickness (SAT) on a predetermined position on the waistline, and its relation to waist measurements as an improvement of metabolic prediction in equally obese subjects. One hundred and forty two consecutive patients were enrolled in the study: stratified by weight as normal (body mass index - BMI 20–25 kg/m2), overweight (BMI 25–30 kg/m2) and obese (BMI >30 kg/m2); and by fasting glucose level as normoglycemic, impaired fasting glucose (IFG), or with type 2 diabetes mellitus (T2DM). SAT was measured in relaxed expiration, 3 cm left of the umbilicus, with ultrasound. Fasting blood samples for glucose, insulin and HbAlc were taken. Waist circumference was slightly higher in the IFG (112.8 cm) and normoglycemic groups (115.62 cm), compared to T2DM (108.15 cm). The T2DM group had a lower average SAT (2.7 cm) than both the IFG group (3.4 cm, p<0.01) and the normoglycemic group (4.2cm, p=0.001). The homeostatic model of assessment for insulin resistance (HOMA IR) was the lowest in normoglycemic and the highest in IFG group. Waistline radius to SAT ratio provides better insight into the deterioration of glucose metabolism than standard anthropometric markers of abdominal obesity in equally obese patients.

Publisher

Journal

Year

Volume

8

Issue

2

Pages

237-243

Physical description

Dates

published
1 - 4 - 2013
online
23 - 1 - 2013

Contributors

author
  • Endocrinology Clinic, Military Medical Academy, Crnotravska 17, 11000, Belgrade, Serbia
  • Centre for Poisoning Control, Military Medical Academy, Crnotravska 17, 11000, Belgrade, Serbia
  • Department of Physiology, Faculty of Medicine, University of Kragujevac, Svetozara Markovica 69, 34000, Kragujevac, Serbia
  • Department of Physiology, Faculty of Medicine, University of Kragujevac, Svetozara Markovica 69, 34000, Kragujevac, Serbia
  • Department of Cardiology, University Hospital Medical Center “Bezanijska kosa”, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
author
  • Dept. of Biochemistry, Military Medical Academy, Crnotravska 17, 11000, Belgrade, Serbia
  • Eye Clinic, Military Medical Academy, Crnotravska 17, 11000, Belgrade, Serbia
  • Institute of Epidemiology, Military Medical Academy, Crnotravska 17, 11000, Belgrade, Serbia

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-012-0119-4
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