Urine saturation and promoter/inhibitor parameters and ratios in renal stone disease caused by ceftriaxone

• Authors: Danko Milošević , Branko Miše , Ivan Habuš , Marija Topalović-Grković , Danica Batinić , Anja Golubić , Daniel Turudić
• Languages of publication: EN

Abstracts

EN

During ceftriaxone treatment of subdural empyema caused by Streptococcus intermedius urinary and biliary stones were noticed. Increased levels of urinary calcium excretion were detected during ongoing treatment in comparison with 2 months check-up. There were no significant changes in the promoter/inhibitor urolithiasis parameters, oxalate, citrate, urate, cistine, glycosaminoglycans or their ratios. Urine saturation was calculated using EQUIL 2 computer programme (calcium oxalate, brushite) and it was normal. Probable trigger for the ceftriaxone/calcium hydroxy carbonate phosphate mixture of stones was a critical boost of solubility products caused by ceftriaxone treatment and phospnate urine content with a subsequent large-scale spontaneous precipitation of crystals.

Keywords

EN

Ceftriaxone; Urolythiasis; Urine saturation; Stone promoters/inhibitors

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2013
• Volume: 8
• Issue: 3
• Pages: 354-357

Dates

published

1 - 6 - 2013

online

17 - 4 - 2013

Contributors

author

Danko Milošević

• Department for Pediatric Nephrology, University Children’s Hospital Zagreb, Zagreb School of Medicine, Kišpatićeva 12, 10000, Zagreb, Croatia

author

Branko Miše

• Department for Pediatric Infectious diseases, School of Medicine, Zagreb University, Zagreb, Croatia

author

Ivan Habuš

• Department for Physical chemistry, Institute „Ruđer Bošković“, Bijenička cesta 54, 10000, Zagreb, Croatia

author

Marija Topalović-Grković

• Department of Anesthesiology and Intesive Care, University Clinical Centre Zagreb, Zagreb, Croatia

author

Danica Batinić

• Department for Pediatric Nephrology, University Children’s Hospital Zagreb, Zagreb School of Medicine, Kišpatićeva 12, 10000, Zagreb, Croatia

author

Anja Golubić

• Department for Pediatric Nephrology, University Children’s Hospital Zagreb, Zagreb School of Medicine, Kišpatićeva 12, 10000, Zagreb, Croatia

author

Daniel Turudić

• Department for Pediatric Nephrology, University Children’s Hospital Zagreb, Zagreb School of Medicine, Kišpatićeva 12, 10000, Zagreb, Croatia

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Identifiers

DOI

10.2478/s11536-012-0091-z