Fluoride bioavailability in saliva during acute psychological stress

• Authors: Ella Naumova , Tudor Sandulescu , Sven Benson , Harald Engler , Manfred Schedlowski , Stefan Zimmer , Peter Gaengler , Michael Thie , Wolfgang Arnold
• Languages of publication: EN

Abstracts

EN

The aim of this study was to investigate the influence of acute stress on salivary fluoride bioavailability. Acute psychological stress was induced using a standardized model of public speaking. The saliva of male subjects was collected before and after the public speaking task and immediately, 10, 30, and 120 minutes after tooth brushing according to the Bass method with a dentifrice containing amine fluoride (AmF) or oral hygiene tablets containing sodium fluoride (NaF). Subjective psychological responses to public speaking were evaluated using the State-Trait Anxiety Inventory (STAI). Saliva cortisol levels were analyzed as an objective stress marker. The saliva secretion rate was measured both before and after public speaking. Saliva fluoride content was measured. Group comparisons were calculated using a univariate analysis of variance (ANOVA). In all analyses, the alpha-level was set at 0.05. Public speaking significantly increased state anxiety (p<0.001) and salivary cortisol concentrations (p<0.001). Acute stress did not influence salivary secretion rates. In the AmF group, stressed individuals exhibited statistically significant (p=0.044) lower fluoride concentration in saliva compared with the nonstressed subjects Acute psychological stress reactions do not cause hyposalivation but decrease fluoride bioavailability after using a dentifrice containing AmF. Fluoride bioavailability during acute stress is dependent on fluoride formulation.

Keywords

EN

Fluoride; Prophylaxis; Caries; Saliva; Cortisol; Stress

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2012
• Volume: 7
• Issue: 4
• Pages: 481-489

Dates

published

1 - 8 - 2012

online

24 - 5 - 2012

Contributors

author

Ella Naumova

• Faculty of Health, School of Dentistry, University of Witten/Herdecke, Witten, Germany

author

Tudor Sandulescu

• Faculty of Health, School of Dentistry, University of Witten/Herdecke, Witten, Germany

author

Sven Benson

• Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany

author

Harald Engler

• Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany

author

Manfred Schedlowski

• Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, Duisburg, Germany

author

Stefan Zimmer

• Faculty of Health, School of Dentistry, University of Witten/Herdecke, Witten, Germany

author

Peter Gaengler

• Faculty of Health, School of Dentistry, University of Witten/Herdecke, Witten, Germany

author

Michael Thie

• Faculty of Health, School of Medicine, University of Witten/Herdecke, Witten, Germany

author

Wolfgang Arnold

• Faculty of Health, School of Dentistry, University of Witten/Herdecke, Witten, Germany

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Identifiers

DOI

10.2478/s11536-012-0021-0