Correlation between total cardiovascular risk and bone density in postmenopausal women

• Authors: Marina Popovic , Ivan Tasić , Aleksandar Dimić , Sonja Stojanović , Bojana Stamenković , Svetlana Kostić , Dejan Popović , Todorka Savić , Nataša Tasić , Snezana Manojlovic , Branislava Ivanović
• Languages of publication: EN

Abstracts

EN

The aim of the paper was to examine the correlation between the total risk of cardiovascular events, determined by the SCORE (Systematic Coronary Risk Evaluation) system, and bone density in postmenopausal women. Examinees and method: The research involved 300 postmenopausal women. On the basis of bone density measurements, the participants were divided into three groups: group I - 84 examinees had osteoporosis, group II - 115 examinees had osteopenia, and group III - 101 examinees had normal bone mineral density (BMD). Results: Participants with high SCORE risk were statistically significantly older compared to low-risk women (60±3 vs. 55±5; p<0.001). They had significantly lower BMD and T scores (−1.09±0.94 vs. −2.86±0.63; p<0.001). Elevation of the SCORE risk by 1% caused a BMD decrease of 0.033 g/cm2(0.029 to 0.036 gr/cm2). Multivariate logistic regression analysis showed that the following factors caused a significant increase in the risk of decreasing BMD: every year of life by 20%, menopause duration by 26%, increase in systolic blood pressure (BP) by 1 mm Hg by 7%, increase in SCORE risk by 1% by 5.31 times, physical inactivity by 5.96 times, and osteoporosis in the family history by 3.91 times. Conclusion: Postmenopausal women who are at high risk for cardiovascular diseases have a lower BMD than those who are not at high risk for cardiovascular diseases.

Keywords

EN

Osteoporosis; Cardiovascular risk; SCORE system

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2011
• Volume: 6
• Issue: 6
• Pages: 795-803

Dates

published

1 - 12 - 2011

online

8 - 10 - 2011

Contributors

author

Marina Popovic

• Health Center Vranje, J. J. Lunge 1, 17500, Vranje, Serbia

author

Ivan Tasić

author

Aleksandar Dimić

author

Sonja Stojanović

author

Bojana Stamenković

author

Svetlana Kostić

author

Dejan Popović

• Health Center Vranje, J. J. Lunge 1, 17500, Vranje, Serbia

author

Todorka Savić

author

Nataša Tasić

• Faculty of Medicine, University of Niš, Bul. Dr Zorana Djindjića 81, 18000, Niš, Serbia

author

Snezana Manojlovic

• Faculty of Medicine, University of Niš, Bul. Dr Zorana Djindjića 81, 18000, Niš, Serbia

author

Branislava Ivanović

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Identifiers

DOI

10.2478/s11536-011-0101-6