A case of almagel-induced methemoglobinemia after pancreatoduodenal resection

• Authors: Jurate Gudaityte , Jurgita Borodiciene , Ricardas Zalys , Danguole Rugyte , Andrius Macas , Tadas Latkauskas
• Languages of publication: EN

Abstracts

EN

We are reporting the case of severe methemoglobinemia resulting from Almagel which was given for treatment of gastrointestinal ulcers after pancreatoduodenal resection. A 64 year old man was treated with Almagel A postoperatively. One day after treatment began, the patient reported what appeared to be cyanotic discolorations of his lips and fingers. (SpO2 80%, normal pO2). Two days later, the patient was diagnosed with methemoglobinemia via co-oximetry and treated with methylene blue. The causes of methemoglobinemia remained unclear, and Almagel A was reinitiated until the second episode of methemoglobinemia, was diagnosed and treated promptly. The dose of benzocaine in Almagel A (100 mg/5 ml) was sufficient enough to cause methemoglobinemia, confirmed using multiwavelength co-oximeter and successfully treated with methylene blue.

Keywords

EN

Adverse drug reactions; Almagel; Methemoglobinemia; Benzocaine

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2011
• Volume: 6
• Issue: 6
• Pages: 773-777

Dates

published

1 - 12 - 2011

online

8 - 10 - 2011

Contributors

author

Jurate Gudaityte

• Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

author

Jurgita Borodiciene

• Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

author

Ricardas Zalys

• Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

author

Danguole Rugyte

• Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

author

Andrius Macas

• Department of Anaesthesiology, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

author

Tadas Latkauskas

• Department of Surgery, Medical Academy, Lithuanian University of Health Sciences, LT 50009, Kaunas, Lithuania

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Identifiers

DOI

10.2478/s11536-011-0100-7