MELAS syndrome mimicking somatoform disorder

• Authors: Gabriella Inczedy-Farkas , Viktoria Remenyi , Agnes Meszaros , Aniko Gal , Gyorgy Blasko , Benjamin Bereznai , Maria Molnar
• Languages of publication: EN

Abstracts

EN

Keywords

EN

Mitochondrial Diseases; MELAS Syndrome; Somatoform Disorders; Disability Evaluation

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2011
• Volume: 6
• Issue: 6
• Pages: 758-761

Dates

published

1 - 12 - 2011

online

8 - 10 - 2011

Contributors

author

Gabriella Inczedy-Farkas

• Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083, Budapest, Hungary

author

Viktoria Remenyi

• Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083, Budapest, Hungary

author

Agnes Meszaros

• Department of Clinical Psychology, Semmelweis University, 1083, Budapest, Hungary

author

Aniko Gal

• Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083, Budapest, Hungary

author

Gyorgy Blasko

• Department of Pharmaceutical Marketing and Management, University of Debrecen Medical and Health Science Center, 4032, Debrecen, Hungary

author

Benjamin Bereznai

• Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083, Budapest, Hungary

author

Maria Molnar

• Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083, Budapest, Hungary

References

• [1] Luft R., Ikkos D., Palmieri G., Ernster L., Afzelius B., A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study. J. Clin. Invest., 1962, 41, 1776–1804 http://dx.doi.org/10.1172/JCI104637[Crossref]
• [2] Gardner A., Boles R.G., Symptoms of somatization as a rapid screening tool for mitochondrial dysfunction in depression. Biopsychosoc. Med., 2008, 2, 7 http://dx.doi.org/10.1186/1751-0759-2-7[Crossref]
• [3] Pieczenik S.R., Neustadt J., Mitochondrial dysfunction and molecular pathways of disease. Exp. Mol. Pathol., 2007, 83, 84–92 http://dx.doi.org/10.1016/j.yexmp.2006.09.008[Crossref]
• [4] Mullick M.S., Nahar J.S., Haq S.A., Psychiatric morbidity, stressors, impact, and burden in juvenile idiopathic arthritis. J. Health. Popul. Nutr., 2005, 23, 142–149
• [5] Gardner A., Boles R.G., Beyond the serotonin hypothesis: Mitochondria, inflammation and neurode-generation in major depression and affective spectrum disorders. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2011, 35, 730–743 http://dx.doi.org/10.1016/j.pnpbp.2010.07.030[WoS][Crossref]
• [6] Quill T.E., Conversion disorder. One of medicine’s blind spots. JAMA, 1985, 254, 3075–3079 http://dx.doi.org/10.1001/jama.254.21.3075[Crossref]
• [7] Stone J., The bare essentials: Functional symptoms in neurology. Pract. Neurol., 2009, 9, 179–189 http://dx.doi.org/10.1136/jnnp.2009.177204[Crossref]
• [8] Mayou R., Levenson J., Sharpe M., Somatoform disorders in DSM-V. Psychosomatics, 2003, 44, 449–451(comment) http://dx.doi.org/10.1176/appi.psy.44.6.449[Crossref]
• [9] Rief W., Isaac M., Are somatoform disorders ‚mental disorders“? A contribution to the current debate. Curr. Opin. Psychiatry, 2007, 20, 143–146 http://dx.doi.org/10.1097/YCO.0b013e3280346999[Crossref][WoS]
• [10] Rief W., Rojas G., Stability of somatoform symptoms-implications for classification. Psychosom. Med., 2007, 69, 864–869 http://dx.doi.org/10.1097/PSY.0b013e31815b006e[Crossref][WoS]
• [11] Stone J., Lafrance W.C., Levenson J.L., Sharpe M., Issues for DSM-5: Conversion disorder. Am. J. Psychiatry, 2010, 167, 626–627 http://dx.doi.org/10.1176/appi.ajp.2010.09101440[Crossref]
• [12] American Psychiatric Association, DSM-5 development, Somatoform Disorders http://www.dsm5.org/ProposedRevisions/Pages/SomatoformDisorders.aspx
• [13] Kanaan R.A., Armstrong D., Wessely S.C., Neurologists’ understanding and management of conversion disorder. J. Neurol. Neurosurg. Psychiatry, 2011, 82, 961–966 http://dx.doi.org/10.1136/jnnp.2010.233114[WoS][Crossref]
• [14] Stone J., Carson A., Aditya H., Prescott R., Zaubi M., Warlow C. et al., The role of physical injury in motor and sensory conversion symptoms: a systematic and narrative review. J. Psychosom. Res., 2009, 66, 383–390 http://dx.doi.org/10.1016/j.jpsychores.2008.07.010[Crossref][WoS]
• [15] Stone J., Smyth R., Carson A., Warlow C., Sharpe M., La belle indifférence in conversion symptoms and hysteria: systematic review. Br. J. Psychiatry, 2006, 188, 204–209 http://dx.doi.org/10.1192/bjp.188.3.204[Crossref]
• [16] Freidl M., Spitzl S.P., Prause W., Zimprich F., Lehner-Baumgartner E., Baumgartner C. et al., The stigma of mental illness: anticipation and attitudes among patients with epileptic, dissociative or somatoform pain disorder. Int Rev. Psychiatry, 2007, 19, 123–129 http://dx.doi.org/10.1080/09540260701278879[Crossref]
• [17] Adams E.F., Lee A.J., Pritchard C.W., White R.J., What stops us from healing the healers: a survey of help-seeking behaviour, stigmatisation and depression within the medical profession. Int. J. Soc. Psychiatry, 2010, 56, 359–370 http://dx.doi.org/10.1177/0020764008099123[Crossref][WoS]
• [18] Aylward M, Locascio JJ. Problems in the assessment of psychosomatic conditions in Social Security benefits and related commercial schemes. J. Psychosom. Res., 1995, 39, 755–765 http://dx.doi.org/10.1016/0022-3999(95)00037-J[Crossref]

Identifiers

DOI

10.2478/s11536-011-0096-z