Investigating gene expression profile of non-small cell lung cancer

• Authors: Tõnu Vooder , Andres Metspalu
• Languages of publication: EN

Abstracts

EN

Lung cancer is mainly a lifestyle-associated disease with poor prognosis and the lowest five year survival rate of all types of cancer. Lung cancers are divided into two main groups: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Surgical treatment is generally indicated in cases of early stage NSCLC, and those patients treated with radical and aggressive surgery have a somewhat better survival rate. The main problems with lung cancer treatment are due to late diagnosis, rapidly developing drug resistance and side effects of the treatment that are experienced by almost all patients. The next step for distinguishing histologically complicated lung cancers and determining optimal treatment strategies is gene expression analysis. Supported by gene expression data, it is possible to prognosticate the course of the disease.

Keywords

EN

Lung cancer; Non-small cell lung cancer; Gene expression; Microchip; Molecular markers

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2011
• Volume: 6
• Issue: 5
• Pages: 608-615

Dates

published

1 - 10 - 2011

online

9 - 8 - 2011

Contributors

author

Tõnu Vooder

author

Andres Metspalu

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Identifiers

DOI

10.2478/s11536-011-0063-8