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Journal

2011 | 6 | 1 | 107-112

Article title

Association between Helicobacter. pylori and coronary artery disease

Content

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EN

Abstracts

EN
The high prevalence of both Helicobacter.pylori infection and coronary atherosclerosis in our country prompted us to assess the probable association between both conditions. This cross-sectional study recruited 153 patients scheduled to undergo coronary artery angiography. Patients were divided into two groups on the basis of coronary angiography results. Sixty-nine patients had coronary atherosclerosis and the 84 remaining patients were normal. Characteristics and pre-angiographic serum levels of triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein, and Helicobacter.pylori IgG antibody were assessed in the patients and compared between the groups. Helicobacter.pylori infection occurred in 88 (57.51%) patients: 40 (58%) in the atherosclerotic group and 48 (57.1%) in the control group with no significant differences (P=0.918). Our multivariable analysis revealed that Helicobacter.pylori infection was not an independent predictive factor for coronary artery disease (P =0.915). Also, the prevalence of atherosclerosis risk factors with respect to the seropositive and seronegative Helicobacter.pylori infection was assessed in the case group, which showed no significant difference. Furthermore, the prevalence of seropositive Helicobacter.pylori infection in terms of the number of diseased coronary vessels was evaluated, this demonstrated no significant association between the number of the diseased vessels and Helicobacter.pylori infection. This study demonstrated that Helicobacter.pylori infection was not an independent predictive factor of atherosclerosis.

Publisher

Journal

Year

Volume

6

Issue

1

Pages

107-112

Physical description

Dates

published
1 - 2 - 2011
online
16 - 12 - 2010

Contributors

  • Infectious Diseases Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, 1411713138, Tehran, Iran
author
  • Cardiovascular Surgery Department, Tehran Heart Center, Tehran University of Medical Sciences, 1411713138, Tehran, Iran
  • Pathology & Laboratory Medicine Department, Tehran Heart Center, Tehran University of Medical Sciences, 1411713138, Tehran, Iran
  • Infectious Diseases Department, Imam Khomeini Hospital, Tehran University of Medical Sciences, 1411713138, Tehran, Iran
author
  • Clinical research Department, Tehran Heart Center, Tehran University of Medical Sciences, 1411713138, Tehran, Iran

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-010-0051-4
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