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Journal

2011 | 6 | 1 | 83-88

Article title

Hospitalized pandemic influenza A (H1N1) patients in a university hospital

Content

Title variants

Languages of publication

EN

Abstracts

EN
The purpose of this study was to describe the demographic and clinical features of hospitalized patients with the pandemic H1N1 influenza A virus infection in a tertiary care hospital in Central Anatolia, Turkey. The patients, all over 16 years of age and hospitalized for influenza-like symptoms between 1 November 2009 and 31 December 2009, were retrospectively identified from the records of the Infectious Diseases Department. Eighty patients whose diagnoses were confirmed by real-time PCR were included in this study. The median age of the patients was 27 years; 41 of them were male. Thirty-seven of the patients had a radiologically proven pneumonia. Eighteen of 37 (48.6%) patients with pneumonia had an underlying co-morbid medical condition, and 14 required intensive care unit admission. Patients with pneumonia had higher levels of C-reactive protein. All patients but one received oseltamivir treatment. Six patients with pneumonia received only antiviral therapy, while 31 of the patients with pneumonia received concomitant antibiotic therapy. Three patients who required mechanical ventilatory support died due to respiratory insufficinency. Although our study implicates the later periods of the pandemic, there were no significant differences for patients’ characteristics between our study and previous reports from the countries where the pandemic first occurred.

Publisher

Journal

Year

Volume

6

Issue

1

Pages

83-88

Physical description

Dates

published
1 - 2 - 2011
online
16 - 12 - 2010

Contributors

author
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
author
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
author
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
  • Department of Internal Medicine, Division of Intensive Care Medicine, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
author
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
author
  • Department of Internal Medicine, Division of Intensive Care Medicine, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey
  • Department of Infectious Diseases and Clinical Microbiology, Erciyes University Faculty of Medicine, 38039, Kayseri, Turkey

References

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  • [2] Swine influenza A (H1N1) infection in two children - Southern California, March–April 2009. MMWR Morb Mortal Wkly Rep 2009;58:400–2
  • [3] Pandemic (H1N1) 2009 - update 86. (http://www.who.int/csr/don/2010_02_5/en/index.html)
  • [4] Ciblak MA, Albayrak N, Odabas Y, Basak Altas A, Kanturvardar M, et al. Cases of influenza A (H1N1) v reported in Turkey, May–July 2009. Euro Surveill 2009;14(32). pii: 19304
  • [5] Bakir M. Pandemic influenza situation update in Turkey. J Infect Dev Ctries 2010;4(2):124–5 http://dx.doi.org/10.3855/jidc.690[Crossref]
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  • [9] Jain S, Kamimoto L, Bramley AM, Schmitz AM, Benoit SR, Louie J, et al. Hospitalized patients with 2009 H1N1 influenza in the United States, April–June 2009. N Engl J Med 2009;361(20):1935–44 http://dx.doi.org/10.1056/NEJMoa0906695[Crossref]
  • [10] Domínguez-Cherit G, Lapinsky SE, Macias AE, Pinto R, Espinosa-Perez L, de la Torre A, et al. Critically III patients with 2009 influenza A (H1N1) in Mexico. JAMA 2009;302(17):1880–7 http://dx.doi.org/10.1001/jama.2009.1536[Crossref]
  • [11] Lapinsky SE. H1N1 novel influenza A in pregnant and immunocompromised patients. Crit Care Med 2010;38(4 Suppl):e52–7 http://dx.doi.org/10.1097/CCM.0b013e3181c85d5f[WoS][Crossref]
  • [12] Yeung JH, Bailey M, Perkins GD, Smith FG. Presentation and management of critically ill patients with influenza A (H1N1): a UK perspective. Crit Care. 2009;13(6):426 http://dx.doi.org/10.1186/cc8151[Crossref]
  • [13] Bacterial coinfections in lung tissue specimens from fatal cases of 2009 pandemic influenza A (H1N1)-United States, May–August 2009. MMWR Morb Mortal Wkly Rep 2009;58:1071–74
  • [14] Ingram PR, Inglis T, Moxon D, Speers D. Procalcitonin and C-reactive protein in severe 2009 H1N1 influenza infection. Intensive Care Med. 2010;36(3):528–32 http://dx.doi.org/10.1007/s00134-009-1746-3[Crossref]
  • [15] Echavarria M, Querci M, Marcone D, Videla C, Martinez A, Bonvehi P, et al. Pandemic (H1N1) 2009 Cases, Buenos Aires, Argentina. Emerg Infect Dis 2010;16(2):311–3 [WoS]
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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-010-0040-7
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