Fluoride bioavailability in saliva using DENTTABS® compared to dentifrice

• Authors: Ella Naumova , Wolfgang Arnold , Peter Gaengler
• Languages of publication: EN

Abstracts

EN

It was the aim of this study to assess fluoride retained in saliva after use of fluoride-containing tablet DENTTABS® compared to toothpaste containing amine fluoride. Four subjects (2 normal saliva secretors, 1 slow secretor, and 1 fast secretor) participated in this crossover study comparing DENTTABS® and ELMEX®. After baseline sample collection, calibrated study personnel brushed the subjects’ teeth with the assigned product for 3 minutes. Saliva samples were taken at baseline (T0), immediately after brushing (T1) and then 10 (T2), 25 (T3) and 85 (T4) minutes post-brushing. The amount of saliva collected was measured, and the fluoride content was analysed. All 4 subjects repeated all study cycles 5 times. Statistical analysis was done using the Mann-Whitney-U test and Spearman correlation. The fluoride retention was significantly higher after brushing with DENTTABS® at T1 and T2. There was a correlation between individual salivary flow rate and the F- content. Flow rate in g/min ranged from 1.1 to 3.8 at T1 and from 0.2 to 1.1 at T4 with much higher F- retention in slow secreting cycles. The saliva fluoride clearance kinetics of two equal amounts of fluoride-containing oral hygiene products demonstrate higher retention for DENTTABS®.

Keywords

EN

Fluoride; Saliva; Dentifrice; Oral hygiene tablets; Bioavailability

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2010
• Volume: 5
• Issue: 3
• Pages: 375-380

Dates

published

1 - 6 - 2010

online

9 - 4 - 2010

Contributors

author

Ella Naumova

• Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany

author

Wolfgang Arnold

• Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany

author

Peter Gaengler

• Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany

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Identifiers

DOI

10.2478/s11536-010-0002-0