Mental retardation and consanguinity in a selected region of the Israeli Arab community

• Authors: Rajach Sharkia , Abdussalam Azem , Qassem Kaiyal , Nathanel Zelnik , Muhammad Mahajnah
• Languages of publication: EN

Abstracts

EN

The prevalence of genetic diseases and congenital malformation in the Israeli Arab community is relatively high, but its distribution is not uniform. The aim of this study was to estimate the frequency of mental retardation disorders in children living in 5 Israeli Arab villages and determine its association with consanguinity. Mental retardation was found to affect 300 children in the screened population, yielding an overall prevalence of 14.5 per 1000. Most of those affected (68%) were the offspring of consanguineous marriages. One village with a high prevalence (4.3%) of neurological hereditary diseases was studied in detail. The prevalence of neurological hereditary diseases and mental retardation associated with consanguinity in these children highlights the need to implement appropriate preventive program.

Keywords

EN

Mental Retardation; Consanguinity; Hereditary diseases

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2010
• Volume: 5
• Issue: 1
• Pages: 91-96

Dates

published

1 - 2 - 2010

online

29 - 1 - 2010

Contributors

author

Rajach Sharkia

author

Abdussalam Azem

• Department of Biochemistry, Faculty of Life Sciences, Tel-Aviv University, 69978, Tel-Aviv, Israel

author

Qassem Kaiyal

• Rappaport Faculty of Medicine, Technion, Child Neurology and Development Center, Carmel Medical Center, 31096, Haifa, Israel

author

Nathanel Zelnik

• Rappaport Faculty of Medicine, Technion, Child Neurology and Development Center, Carmel Medical Center, 31096, Haifa, Israel

author

Muhammad Mahajnah

• Rappaport Faculty of Medicine, Technion, Child Neurology and Development Center, Carmel Medical Center, 31096, Haifa, Israel

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Identifiers

DOI

10.2478/s11536-009-0112-8