A case of ichthyosiform sarcoidosis with unusual localization

• Authors: Salim Tekin , Kerim Cayir , Mehmet Bilici , Sare Şipal , Mustafa Atasoy , Mehmet Türkeli
• Languages of publication: EN

Abstracts

EN

Sarcoidosis is a systemic granulomatous disease of unknown cause that commonly involves the lungs, lymph nodes, bones, liver, spleen, or skin. Cutaneous findings of sarcoidosis occur in 20% to 35% of patients with systemic disease. The recognition of cutaneous lesions is important, because it gives important clues to diagnosis and also allows for easy biopsy. We report a 71-year-old Turkish woman with erythematous lesions, which included widespread, erythematous macules of various sizes on the chest, abdomen, and back on both sides of her body. Fine white scales covered some of the lesions. Hepatomegaly and bilateral hilar lymphadenopathy were also observed. Biopsy specimens of the skin showed dermal, noncaseating, epitheloid granulomas. The diagnosis, based on correlation of the clinical presentation and histopathological findings, was ichthyosiform sarcoidosis with systemic involvement. The difference between our case and other cases of ichthyosiform sarcoidosis described in the literature is that ours involved only the trunk and not the extremities. We are presenting this case because it is an interesting and rare variant of ichthyosiform sarcoidosis.

Keywords

EN

Sarcoidosis; Ichthyosiform eruption; Skin lesions

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2009
• Volume: 4
• Issue: 3
• Pages: 388-390

Dates

published

1 - 9 - 2009

online

3 - 7 - 2009

Contributors

author

Salim Tekin

• Division of Medical Oncology, Department of Internal Medicine, 25240, Erzurum, Turkey

author

Kerim Cayir

• Division of Medical Oncology, Department of Internal Medicine, 25240, Erzurum, Turkey

author

Mehmet Bilici

• Division of Medical Oncology, Department of Internal Medicine, 25240, Erzurum, Turkey

author

Sare Şipal

• Department of Pathology, Atatürk University, School of Medicine, 25240, Erzurum, Turkey

author

Mustafa Atasoy

• Department of Dermatology, 25240, Erzurum, Turkey

author

Mehmet Türkeli

• Division of Medical Oncology, Department of Internal Medicine, 25240, Erzurum, Turkey

References

• [1] Kerdel FA., Moschella SL., Sarcoidosis: an updated rewiew, J. Am. Acad. Dermatol., 1984, 11,1–19 http://dx.doi.org/10.1016/S0190-9622(84)70133-2[Crossref]
• [2] Mountcastle ME., Lupton GP., An Ichthyosiform Euption on the Legs, Arch. Dermatol, 1989, 125(10), 1415–1416, 1419 http://dx.doi.org/10.1001/archderm.125.10.1415[Crossref]
• [3] Lupton JR., Figueroa P., Berberian BJ et al., Can granuloma annulare evolve into cutaneus sacoidosis? Cutis., 2000,66(5),390–392
• [4] Cather JC., Cohen PR., Ichthyosiform sarcoidosis, J. Am. Acad. Dermatol., 1999, 40(5 pt 2), 862–865
• [5] Bense-Kupin L., Pelachyk JM., Ichthyosiform sarcoidosis, Report of two cases and rewiew of the literature, J. Am. Acad. Dermatol., 1987, 17(4),616–620 http://dx.doi.org/10.1016/S0190-9622(87)70246-1[Crossref]
• [6] Matarasso SL., Bruce S., Ichthyosiform sarcoidosis: report of a case, Cutis., 1991, 47(6),405–408 [PubMed]
• [7] Paller AS., Roenigk AH Jr., Caro WA., Extensive ichthyosiform sarcoidosis in a patient with juvenile rheumatoid arthritis, Arch. Dermatol., 1985,121(2), 171–172 http://dx.doi.org/10.1001/archderm.121.2.171[Crossref]
• [8] Mallory SB., Paller AS., Ginsburg BC., et al., Sarcoidosis in children: differentiation from juvenile rheumatoid arthritis, Pediatr. Dermatol., 1987, 4(4),313–319 http://dx.doi.org/10.1111/j.1525-1470.1987.tb00799.x[Crossref]
• [9] Feind-Koopmans AG., Lucker GP., van de Kerkhof PC., Acquired ichthyosiform erythroderma and sarcoidosis, J. Am. Acad. Dermatol., 1996, 35(5 pt 2),826–828 http://dx.doi.org/10.1016/S0190-9622(96)90094-8[Crossref]
• [10] Kauh YC., Goody HE., Luscombe HA., Ichthyosiform sarcoidosis, Arch. Dermatol. 1978, 114 (1), 100–101 http://dx.doi.org/10.1001/archderm.114.1.100[Crossref]
• [11] Mora RG., Gullung WH., Sarcoidosis: a case with unusual manifestations, South. Med. J., 1980, 73(8),1063–1065
• [12] Matsuoka LY., LeVine M., Glasser S., et al., Ichthyosiform sarcoid, Cutis.,1980, 25(2), 188–189 [PubMed]

Identifiers

DOI

10.2478/s11536-009-0037-2