Antimicrobial resistance in bacteria

• Authors: Katrijn Bockstael , Arthur Aerschot
• Languages of publication: EN

Abstracts

EN

The development of antimicrobial resistance by bacteria is inevitable and is considered as a major problem in the treatment of bacterial infections in the hospital and in the community. Despite efforts to develop new therapeutics that interact with new targets, resistance has been reported even to these agents. In this review, an overview is given of the many therapeutic possibilities that exist for treatment of bacterial infections and how bacteria become resistant to these therapeutics.

Keywords

EN

Antimicrobial agents; Resistance development; Efflux; Alteration of drug target; Antibacterials

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2009
• Volume: 4
• Issue: 2
• Pages: 141-155

Dates

published

1 - 6 - 2009

online

27 - 3 - 2009

Contributors

author

Katrijn Bockstael

• Laboratory for Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000, Leuven, Belgium

author

Arthur Aerschot

• Laboratory for Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000, Leuven, Belgium

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Identifiers

DOI

10.2478/s11536-008-0088-9