Carcinosarcoma of the spleen: literature review of a very rare tumour

• Authors: Annapurna Rao , George Mathew , Kalimuthu Marimuthu , Urmila Pandey , Jane Worlding
• Languages of publication: EN

Abstracts

EN

Carcinosarcomas are rare tumours, which have both epithelial, and connective tissue elements. They are most commonly seen in the female genital tract. Rarely they arise from the gastrointestinal tract. We report a case of Carcinosarcoma arising as a primary in the spleen of a male aged 60yrs. The most unique feature of this tumour is the presence of osteosarcomatous element. This report highlights the importance of clinical awareness of such rare tumours and gives a brief overview on presentation, probable aetiology, diagnosis and management with literature review of carcinosarcoma.

Keywords

EN

Carcinosarcoma; Sarcomatoid Carcinoma; Colorectal neoplasm; Spleen; beta hCG; Germ Cell Tumour

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2007
• Volume: 2
• Issue: 2
• Pages: 230-235

Dates

published

1 - 6 - 2007

online

1 - 6 - 2007

Contributors

author

Annapurna Rao

• Department of Surgery and Pathology (Colorectal Unit), George Eliot Hospital, Nuneaton, UK

author

George Mathew

• Department of Surgery and Pathology (Colorectal Unit), George Eliot Hospital, Nuneaton, UK

author

Kalimuthu Marimuthu

• Department of Surgery and Pathology (Colorectal Unit), George Eliot Hospital, Nuneaton, UK

author

Urmila Pandey

• Department of Surgery and Pathology (Colorectal Unit), George Eliot Hospital, Nuneaton, UK

author

Jane Worlding

• Department of Surgery and Pathology (Colorectal Unit), George Eliot Hospital, Nuneaton, UK

References

• [1] T.A. Steeper, F. Piscioli and J. Rosai: “Squamous cell carcinoma with sarcoma like stroma of the female genital tract”: Clinicopathologic study of four cases, Cancer, Vol. 52, (1983), pp. 890–898. http://dx.doi.org/10.1002/1097-0142(19830901)52:5<890::AID-CNCR2820520525>3.0.CO;2-T[Crossref]
• [2] N. Weidner and P. Zekan: “Carcinosarcoma of colon”, Report of a unique case with light and immunohistochemical studies, Cancer, Vol. 58, (1986), pp. 1126–1130. http://dx.doi.org/10.1002/1097-0142(19860901)58:5<1126::AID-CNCR2820580525>3.0.CO;2-Q[Crossref]
• [3] G. Isimbaldi, M. Sironi and A. Assi: “Sarcomatoid Carcinoma of the colon”; Report of second case with Immunohistochemical study, Path. Res. Pract., Vol. 192, (1996), pp. 483–487.
• [4] T. Aramendi, M.J. Fernandez-Acenero and M.C. Villanueva: “Carcinosarcoma of the colon report of a rare tumour”, Path. Res. Pract., Vol. 199(5), (2003) pp. 345–348. http://dx.doi.org/10.1078/0344-0338-0428[Crossref]
• [5] W.H. Westra, B.O. Anderson and D.S. Klimstra: “Carcinosarcoma of the spleen”, Am. J. Surg. Pathol., Vol. 18(3), (1994), pp. 309–315. http://dx.doi.org/10.1097/00000478-199403000-00012[Crossref]
• [6] S. Morinaga, R. Ohyama and J. Koizumi: “Low grade Mcinouscystadenocarcinoma in the spleen”, Am. J. Surg. Pathol., Vol. 16, (1992), pp. 903–908. http://dx.doi.org/10.1097/00000478-199209000-00009[Crossref]
• [7] A. Nakao, K. Sakagami, M. Uda, S. Mitsuoka and H. Ito: “Carcinosarcoma of the colon”, J. Gastroenterol., Vol. 33, (1998), pp. 276–279. http://dx.doi.org/10.1007/s005350050083[Crossref]
• [8] B. Leidinger, S. Bielack, G. Koehler and V. Vieth: “High level of beta hCG stimulating pregnancy in recurrent osteosarcoma”; Case report and review of literature, J. Can. Res. Clin. Oncol., Vol. 130, (2004), pp. 357–361. http://dx.doi.org/10.1007/s00432-004-0541-3[Crossref]

Identifiers

DOI

10.2478/s11536-007-0011-9