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Number of results

Journal

2014 | 12 | 8 | 837-850

Article title

Influence of vegetable oil on the synthesis of bioactive nanocarriers with broad spectrum photoprotection

Content

Title variants

Languages of publication

EN

Abstracts

EN
Due to their unique features, most nanostructured lipid carriers (NLCs) in association with vegetable oils that exhibit UV filtering properties and bioactivity could be used in many cosmetic formulations. Therefore, in this work, a new application of pomegranate seed oil (PSO) in the cosmetic sector was developed, based on the synthesis of bioactive lipid nanocarriers loaded with various UV filters by the hot high pressure homogenization technique. To get broad spectrum photoprotection, different UVA and UVB filters have been used (Avobenzone - AVO, Octocrylen-OCT, Bemotrizinol - BEMT). The influence of the solid lipids combined with PSO on the particle size, physical stability and entrapment efficiency was investigated using 8 nanocarrier systems. An improved physical stability and an appropriate size were obtained for NLCs prepared with Emulgade, carnauba wax and PSO (e.g. −30.9÷-36.9 mV and 160÷185 nm). NLCs showed an entrapment efficiency above 90% and assured slow release rates of UV filters, especially for BEMT (5%). The developed nanocarriers have been formulated into safe and effective sunscreens containing low amounts of synthetic UV filters coupled with a high percent of natural ingredients. The highest SPF of 34.3 was obtained for a cream comprising of 11% PSO and 3.7% BEMT

Publisher

Journal

Year

Volume

12

Issue

8

Pages

837-850

Physical description

Dates

published
1 - 8 - 2014
online
1 - 5 - 2014

Contributors

  • “Politehnica” University of Bucharest
  • “Politehnica” University of Bucharest
  • “Politehnica” University of Bucharest
  • “Politehnica” University of Bucharest
author
  • “Politehnica” University of Bucharest

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-014-0503-9
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