Potentiometric cholesterol biosensing application of graphene electrode with stabilized polymeric lipid membrane

• Authors: Georgia-Paraskevi Nikoleli , Zafar Ibupoto , Dimitrios Nikolelis , Vlassis Likodimos , Nikolas Psaroudakis , Nikolaos Tzamtzis , Magnus Willander , Tibor Hianik
• Languages of publication: EN

Abstracts

EN

Abstract A novel potentiometric cholesterol biosensor has been fabricated through the immobilization of the stabilized polymeric lipid membrane onto graphene electrode. The stabilized polymeric lipid membrane is composed of cholesterol oxidase enzyme and polymerization mixture; which holds paramount influence on the properties of the cholesterol biosensor. The presented biosensor reveals an appreciable reproducibility, good selectivity and high sensing capability with a linear slope curve of ∼64 mV per decade. The strong biocompatibility among stabilized polymeric lipid membranes and human biofluids provides the possibility to use for real blood samples and other biological applications. Graphical abstract [...]

Keywords

EN

Graphene; Potentiometric sensor; Cholesterol Oxidase; Cholesterol; Stabilized Polymeric Lipid Membrane

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2013
• Volume: 11
• Issue: 9
• Pages: 1554-1561

Dates

published

1 - 9 - 2013

online

29 - 6 - 2013

Contributors

author

Georgia-Paraskevi Nikoleli

• Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Dept 1, Chemical Sciences, National Technical University of Athens, GR-157 80, Athens, Greece

author

Zafar Ibupoto

• Department of Science and Technology, Linköping University, Campus Norrköping, SE-60174, Norrköping, Sweden

author

Dimitrios Nikolelis

• Laboratory of Environmental Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis-Kouponia, GR-15771, Athens, Greece

author

Vlassis Likodimos

• Institute of Advanced Materials, Physicochemical Processes, Nanotechnology and Microsystems — Division of Physical Chemistry, NCSR “Demokritos”, Aghia Paraskevi Attikis, GR-15341, Athens, Greece

author

Nikolas Psaroudakis

• Laboratory of Inorganic Chemistry, Department of Chemistry, University of Athens, Panepistimiopolis-Kouponia, GR-15771, Athens, Greece

author

Nikolaos Tzamtzis

• Laboratory of Inorganic & Analytical Chemistry, School of Chemical Engineering, Dept 1, Chemical Sciences, National Technical University of Athens, GR-157 80, Athens, Greece

author

Magnus Willander

• Department of Science and Technology, Linköping University, Campus Norrköping, SE-60174, Norrköping, Sweden

author

Tibor Hianik

• Faculty of Mathematics, Physics and Informatics, Comenius University, 84248, Bratislava, Slovakia

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Identifiers

DOI

10.2478/s11532-013-0285-5