Recentchiral selectors for separation in HPLC and CE

• Authors: Květa Kalíková , Martina Riesová , Eva Tesařová
• Languages of publication: EN

Abstracts

EN

Enantiomers (stereoisomers) can exhibit substantially different properties if present in chiral environments. Since chirality is a basic property of nature, the different behaviors of the individual enantiomers must be carefully studied and properly treated. Therefore, enantioselective separations are a very important part of separation science. To achieve the separation of enantiomers, an enantioselective environment must be created by the addition of a chiral selector to the separation system. Many chiral selectors have been designed and used in various fields, such as the analyses of drugs, food constituents and agrochemicals. The most popular have become the chiral selectors and/or chiral stationary phases that are of general use, i.e., are applicable in various separation systems and allow for chiral separation of structurally different compounds. This review covers the most important chiral selectors / chiral stationary phases described and applied in high performance liquid chromatography and capillary electrophoresis during the period of the last three years (2008–2011). [...]

Keywords

EN

High performance liquid chromatography; Capillary electrophoresis; Chiral selector; Chiral stationary phase; Enantioselective separation

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2012
• Volume: 10
• Issue: 3
• Pages: 450-471

Dates

published

1 - 6 - 2012

online

23 - 3 - 2012

Contributors

author

Květa Kalíková

• Department of Physical and Macromolecular Chemistry, Charles University in Prague, Faculty of Science, 128 43, Prague 2, Czech Republic

author

Martina Riesová

• Department of Physical and Macromolecular Chemistry, Charles University in Prague, Faculty of Science, 128 43, Prague 2, Czech Republic

author

Eva Tesařová

• Department of Physical and Macromolecular Chemistry, Charles University in Prague, Faculty of Science, 128 43, Prague 2, Czech Republic

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Identifiers

DOI

10.2478/s11532-011-0142-3