PXPd-catalyzed borylation of aniline derivatives

• Authors: Susan Wheaton , S. Humanayun Kabir , Haiwen Zhang , Christopher Vogels , Andreas Decken , Stephen Westcott
• Languages of publication: EN

Abstracts

EN

Addition of pinacolborane (HBO2C2Me4) to 2-iodoaniline can be catalyzed using a number of palladium complexes, including [(t-Bu)2PCl]2PdCl2 (PXPd), to give the corresponding boronate ester 2-H2NC6H4(BO2C2Me4) in excellent yields. The PXPd system could also be used in the catalyzed borylation of substituted anilines to give the corresponding aminoboronate esters in moderate to high yields. [...]

Keywords

EN

Boron; Borylation; Catalysis; Cross-coupling; Palladium

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2010
• Volume: 8
• Issue: 4
• Pages: 725-731

Dates

published

1 - 8 - 2010

online

17 - 6 - 2010

Contributors

author

Susan Wheaton

• Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

author

S. Humanayun Kabir

• Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

author

Haiwen Zhang

• Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

author

Christopher Vogels

• Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

author

Andreas Decken

• Department of Chemistry, University of New Brunswick, Fredericton, NB, E3B 5A3, Canada

author

Stephen Westcott

• Department of Chemistry and Biochemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

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Identifiers

DOI

10.2478/s11532-010-0076-1